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. Author manuscript; available in PMC: 2014 May 21.
Published in final edited form as: Pain. 2006 Dec 6;129(0):143–154. doi: 10.1016/j.pain.2006.10.009

Table 1.

Mean Number of Profiles Expressing FOS in the Spinal Dorsal Horn

SNL-
Ipsilateral		 SNL -
Contralateral		 Sham - Ipsilateral Sham -
Contralateral
L4 I–II 12.4 ± 1.4 4.7 ± 1.0 4.1 ± 1.1 2.1 ± 0.5
III–IV 30.8 ± 2.4* 17.1 ± 1.2 11.4 ± 1.1 10.2 ± 0.8
V–VI 13.2 ± 2.7 6.9 ± 1.2 3.8 ± 0.6 3.1 ± 0.9
Total 55.6 ± 5.1* 28.7 ± 2.7 17.8 ± 1.4 15.3 ± 1.5
L5 I–II 12.4 ± 1.4 4.7 ± 1.0 4.5 ± 0.6 3.0 ± 0.7
III–IV 34.0 ± 2.4* 17.9 ± 1.2 14.2 ± 2.1 13.4 ± 1.6
V–VI 16.8 ± 2.4 10.0 ± 1.5 3.1 ± 0.8 2.4 ± 0.7
Total 64.3 ± 4.9* 35.2 ± 3.1 21.3 ± 2.5 19.3 ± 2.0
L6 I–II 8.6 ± 1.3 3.4 ± 0.7 4.4 ± 0.6 4.1 ± 0.7
III–IV 31.9 ± 3.0* 16.4 ± 1.2 10.2 ± 0.5 9.8 ± 1.4
V–VI 16.4 ± 1.9 6.6 ± 1.2 3.4 ± 1.1 3.0 ± 1.0
Total 57.6 ± 5.0* 26.4 ± 2.3 17.3 ± 1.1 16.9 ± 2.3

Gentle mechanical stimulation of the hindpaw evokes FOS expression in the lumbar dorsal horn. FOS expression in laminae III–IV ipsilateral to SNL is significantly (* p < 0.05) increased when compared to the contralateral side.