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. Author manuscript; available in PMC: 2015 Apr 14.
Published in final edited form as: Chembiochem. 2014 Mar 19;15(6):815–821. doi: 10.1002/cbic.201300756

Scheme 1.

Scheme 1

Bisindolylmaleimide compounds, with the 3,4-di-1H-indol-3-yl-1H-pyrrole-2,5-dione core structure colored in red. A) Synthetic derivatives that have entered into clinical trials for drug therapy. B) Compounds that are encoded by the eDNA-derived mar biosynthetic gene cluster.