Table V.
Effect of isolation protocol on final viable cell yield and success rate of hepatocyte isolations from different types of liver tissue.
| Disease type | Final viable cell yield/g tissue, ×104 |
Success |
||
|---|---|---|---|---|
| Old protocol | New protocol | Old protocol | New protocol | |
| ALD | 0.26 (0.00–0.90) | 9.83 (3.51–31.61) | 0% | 63% |
| Biliary cirrhosis | 10.59 (5.48–20.34) | 29.12 (17.23–85.78) | 60% | 71% |
| Resected | 9.48 (0.00–20.39) | 61.88 (52.26–97.54) | 33% | 100% |
| Normal/donor | 11.52 (4.88–24.76) | 16.57 (9.31–38.55) | 60% | 83% |
Data displayed as median (quartiles) for continuous variables.