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. Author manuscript; available in PMC: 2014 May 22.
Published in final edited form as: Biomaterials. 2011 Oct 10;33(1):247–255. doi: 10.1016/j.biomaterials.2011.09.026

Fig. 1.

Fig. 1

Synthesis of the Gd(III)-DOTA-DSPE microbubble shells using the post-labeling technique: (i) 100 M excess DOTA-NHS, pH 8.5; (ii) 20 M excess GdCl3, pH 5.6, T = 50 or 70 °C; (iii) storage at pH 7.4.