Table 2.
Tract | Segment | Controls | Preterm |
ANCOVA [1] |
ANCOVA [2] |
||||
---|---|---|---|---|---|---|---|---|---|
Unimpaired language | Impaired language | Covariates: age and sex/age, sex and ICV | Post hoc: preterm groups | Covariate: age, sex, total WM | Post hoc: preterm groups | ||||
Left AF | Direct | Volume (cm3) | 11.8 (2.3) | 11.1(2.6) | 9.6 (2.9)* | F(2,71) = 2.3, P = 0.117 | P = 0.093 | F(2,71) = 0.4, P = 0.694 | P = 0.451 |
FA | 0.284 (0.02) | 0.295 (0.02) | 0.286 (0.02) | F(2,73) = 1.5, P = 0.237 | P = 0.369 | - | - | ||
Anterior | Volume (cm3) | 8.2 (2.2) | 9.2 (3.5) | 8.2 (3.1) | F(2,70) = 0.9, P = 0.390 | P = 0.476 | F(2,70) = 0.7, P = 0.490 | P = 0.337 | |
FA | 0.286 (0.02) | 0.284 (0.02) | 0.282 (0.03) | F(2,71) = 0.3, P = 0.719 | P = 0.718 | - | - | ||
Posterior | Volume (cm3) | 4.2 (2.8) | 4.7 (3.3) | 4.8 (3.3) | F(2,70) = 0.4, P = 0.656 | P = 0.751 | F(2,70) = 0.3, P = 0.745 | P = 0.787 | |
FA | 0.342 (0.03) | 0.346 (0.04) | 0.339 (0.03) | F(2,71) = 0.2, P = 0.799 | P = 0.525 | - | - | ||
Right AF | Direct | Volume (cm3) | 10.89 (2.3) | 10.82 (2.3) | 9.29 (1.9)* | F(2,71) = 2.1, P = 0.131 | P = 0.047 | F(2,70) = 0.9, P = 0.38 | P = 0.191 |
FA | 0.28 (0.02) | 0.29 (0.02) | 0.28 (0.02) | F(2,70) = 1.2, P = 0.305 | P = 0.438 | - | - | ||
Anterior | Volume (cm3) | 13.0 (2.2) | 12.5 (2.5) | 12.4 (3.7) | F(2,71) = 0.06, P = 0.945 | P = 0.747 | F(2.70) = 0.3, P = 0.750 | P = 0.492 | |
FA | 0.279 (0.02) | 0.280 (0.02) | 0.269 (0.02) | F(2,70) = 1.6, P = 0.205 | P = 0.105 | - | - | ||
Posterior | Volume (cm3) | 3.8 (2.7) | 4.7 (3.2) | 4.9 (2.7) | F(2,71) = 0.5, P = 0.624 | P = 0.902 | F(2,70) = 0.8, P = 0.442 | P = 0.738 | |
FA | 0.341 (0.04) | 0.342 (0.04) | 0.327 (0.04) | F(2,70) = 1.0, P = 0.360 | P = 0.177 | - | - | ||
Left UF/ECFS | Volume (cm3) | 5.1 (2.2) | 3.7 (1.8) | 2.5 (1.5)** | F(2,71) = 7.2, P = 0.001 | P = 0.014 | F(2,70) = 4.1, P = 0.020 | P = 0.042 | |
FA | 0.261 (0.02) | 0.260 (0.02) | 0.260 (0.02) | F(2,70) = 0.005, P = 0.995 | P = 0.992 | - | - | ||
Right UF/ECFS | Volume (cm3) | 5.7 (1.8) | 4.9 (2.1) | 3.2 (1.7)*** | F(2,71) = 6.5, P = 0.003 | P = 0.003 | F(2,70) = 4.0, P = 0.023 | P = 0.011 | |
FA | 0.254 (0.02) | 0.253 (0.02) | 0.253 (0.01) | F(2,70) = 0.05, P = 0.947 | P = 0.895 | - | - |
Table displays mean unadjusted values and standard deviation in parenthesis. Value in bold are significant.
Different from controls *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, - = not performed.
AF = arcuate fasciculus; FA = fractional anisotropy; ICV = intracranial volume; WM = white matter volume; UF/ECFS = uncinate fasciculus/ extreme capsule fibre system.