Skip to main content
The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2014 May 9;289(19):13362. doi: 10.1074/jbc.A112.447359

Tyrosine sulfation of chemokine receptor CCR2 enhances interactions with both monomeric and dimeric forms of the chemokine monocyte chemoattractant protein-1 (MCP-1).

Joshua H Y Tan, Justin P Ludeman, Jamie Wedderburn, Meritxell Canals, Pam Hall, Stephen J Butler, Deni Taleski, Arthur Christopoulos, Michael J Hickey, Richard J Payne, Martin J Stone
PMCID: PMC4036344

VOLUME 288 (2013) PAGES 10024–10034

The panels labeled R2B in Fig. 3 should have been labeled R2C and vice versa. Similarly, the Kd values listed in Table 2 for R2B and R2C should be reversed. The corrected data are inconsistent with the speculation (page 10030) that the chemokine may have evolved to be optimally responsive (in terms of dimer dissociation) to the biologically dominant form of the receptor but do not change the main conclusions of this work.


Articles from The Journal of Biological Chemistry are provided here courtesy of American Society for Biochemistry and Molecular Biology

RESOURCES