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. Author manuscript; available in PMC: 2014 May 29.
Published in final edited form as: Hypertension. 2013 Jan 7;61(2):400–407. doi: 10.1161/HYPERTENSIONAHA.111.00221

Figure 7.

Figure 7

Renin immunohistochemistry (white) in kidney sections of untreated Ren1d+/Cre–NO-sensitive guanylate cyclase (NO-GC)fl/ fl mice (A) and Ren1d+/Cre–NO-GCfl/fl mice treated with low-salt (LS) diet+enalapril for 3 weeks (B). aff. art. indicates afferent arteriole; CLS, renin cells forming cuff-like structures; and G, glomeruli. Arrows indicate afferent arteriole. 3D-reconstruction of α-smooth muscle actin (α-SMA; grey) and of renin-immunoreactive areas (black) in kidneys of mice lacking endothelial isoform of nitric oxide synthase (eNOS−/−) before (C) and after receiving a LS diet+enalapril for 3 weeks (D).