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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Virology. 2014 Jan 9;0:243–249. doi: 10.1016/j.virol.2013.12.029

Figure 3. Vaccine immunogenicity and efficacy in a long-term study.

Figure 3

[A] VNA titers after immunization: Groups of 6 animals were vaccinated with 109 vp of AdC68rab.gp. The rabies VNA titers were tested periodically from sera for a period of 21 months. The graph shows rabies VNA titers of individual animals. [B] Vaccine efficacy: The vaccinated animals shown in [A] were challenged with canine rabies virus at 22 months after immunization. An additional 5 unvaccinated animals were challenged as well. Survival was recorded. [C] VNA titers after challenge. Sera from the vaccinated animals in [A] were tested the day of challenge and then at the indicated time points after challenge for VNA titers to rabies virus. The graph shows rabies VNA titers of individual animals. [NB: need to change the number of controls in B from 6 to 5.