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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Cancer. 2014 Mar 25;120(12):1800–1809. doi: 10.1002/cncr.28646

Table 1.

Association of clinicopathologic features with time to biochemical failure using univariate Cox regression models

Variable N % HR (95%CI) P-value
Total population 96
Gleason score 0.937
 3+4 63 41.2 0.96 (0.32–2.88)
 4+3 33 21.6 1.00
Pathologic stage 0.036
 Extraprostatic extension (pT3+) 22 22.9 3.26 (1.08–9.80)
 Prostate-limited (pT2) 74 77.1 1.00
Lymph node involvement 0.116
 Yes (pN1) 3 3.1 3.52 (0.74–16.81)
 No (pN0) 93 96.9 1.00
Surgical margin involvement 0.016
 Yes (pR1) 40 41.7 4.86 (1.35–17.54)
 No (pR0) 56 58.3 1.00
Non-Localized Tumor Indicator* 0.022
 Yes 50 52.1 5.75 (1.28–25.74)
 No 46 47.9 1.00
N Mean (SD) HR (95%CI) P-value

Age (years) 90 61.1 (6.6) 1.05 (0.97–1.14) 0.257
Pre-operative PSA (ng/mL) 96 7.4 (5.2) 1.06 (1.00–1.13) 0.070
*

Non-Localized Tumor Indicator is a summary metric of tumor confined to prostate. ‘Yes’ indicates extraprostatic extension (pathologic stage pT3+), involved lymph nodes (pN1), and/or positive surgical margins (pR1).