Table 2.

Biomarkers as predictors of time to biochemical failure using Cox regression models

Variable			Univariate				Multivariate*
	N-total	N-events	HR (95%CI)	P-value	N-total	N-events	HR (95%CI)	P-value
HAS2	93	14	1.29 (0.73–2.27)	0.381	87	13	1.66 (0.90–3.03)	0.102
HA	94	15	1.66 (0.97–2.83)	0.065	88	14	1.74 (1.01–2.99)	0.047
HYAL1	93	13	1.54 (0.88–2.68)	0.131	87	12	1.63 (0.86–3.12)	0.136
CD44	92	13	0.87 (0.50–1.54)	0.642	86	12	0.75 (0.42–1.35)	0.339
CD44v6	91	13	1.24 (0.77–2.00)	0.376	85	12	1.34 (0.79–2.26)	0.282
HMMR	89	13	2.00 (1.08–3.71)	0.028	83	12	2.03 (1.04–3.99)	0.040

^*Adjusted for age at prostatectomy, preoperative PSA, primary Gleason pattern, and Non-Localized Tumor Indicator.