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. Author manuscript; available in PMC: 2014 Jun 6.
Published in final edited form as: Ultrasonics. 2013 Jul 11;54(1):177–186. doi: 10.1016/j.ultras.2013.06.008

Fig. 6.

Fig. 6

Dynamic changes in echogenicity after administering different anti-inflammatory drugs to the same fracture mice were observed by daily feeding the aspirin (Asp), indomethacin (IND), or selective COX-2 inhibitor (SC-236). Asp treatment prohibited fracture-induced echogenicity on post-fracture day seven. Ultrasonographic of IND treated mice promoted the occurrence of hyperechogenic image at two days post fracture. *: significant difference (P < .05) from the referred ROI before fracture. &: significant difference (P < .05) from the referred ROI in the time-matched fracture mice without drug treatment.