Figure 3.

DS-SILY₂₀ regulates PDGF- or IFN-γ-induced SMC migration. Migration of (A, B) proliferative and (C, D) quiescent SMCs treated with 10 ng/mL (A, C) PDGF or (B, D) IFN-γ with or without DS-SILY₂₀. SMC migration was examined via a modified Boyden chamber, where SMCs were treated with PDGF or IFN-γ with or without DS-SILY₂₀. Following incubation, cells were fixed formaldehyde and nuclei stained with Hoechst, to identify migratory SMCs. * Represents significance from control nontreated cells; # represents significance either PDGF- or IFN-γ-treated cultures (N > 6).