Table 1. Clinicopathological features of 78 patients with high and low heat shock protein 90 (HSP90)-expressing mass-forming cholangiocarcinomas.
| Factor | HSP90 high (n = 55) | HSP90 low (n = 23) | P |
|---|---|---|---|
| Age (years) | 58.3 ± 12.2 | 63.2 ± 10.9 | 0.086 |
| Gender | 0.713 | ||
| Male | 24 (43.6) | 9 (39.1) | |
| Female | 31 (56.4) | 14 (60.9) | |
| Symptom | 0.097 | ||
| Positive | 44 (80.0) | 22 (95.7) | |
| Negative | 11 (20.0) | 1 (4.3) | |
| AST (IU/L) | 0.564 | ||
| ≤ 34 | 29 (52.7) | 10 (45.5) | |
| > 34 | 26 (47.3) | 12 (54.5) | |
| ALT (U/L) | 0.357 | ||
| ≤ 36 | 27 (52.9) | 13 (65.0) | |
| > 36 | 24 (47.1) | 7 (35.0) | |
| ALP (U/L) | 0.491 | ||
| ≤ 94 | 15 (28.3) | 8 (36.4) | |
| > 94 | 38 (71.7) | 14 (63.6) | |
| Bilirubin (total) (mg/dL) | 0.934 | ||
| ≤ 1.3 | 45 (81.8) | 19 (82.6) | |
| > 1.3 | 10 (18.2) | 4 (17.4) | |
| Albumin (g/dL) | 0.226 | ||
| ≤ 3.5 | 13 (26.5) | 9 (40.9) | |
| > 3.5 | 36 (73.5) | 13 (59.1) | |
| Serum CEA (ng/mL) | 0.984 | ||
| ≤ 5 | 17 (44.7) | 8 (44.4) | |
| > 5 | 21 (55.3) | 10 (55.6) | |
| Size (cm) | 0.843 | ||
| ≤ 5 | 23 (43.4) | 9 (40.9) | |
| > 5 | 30 (56.6) | 13 (59.1) | |
| Lymph node | 0.076 | ||
| Negative | 38 (69.1) | 11 (47.8) | |
| Positive | 17 (30.9) | 12 (52.2) | |
| Differentiated | 0.131 | ||
| Well | 1 (1.8) | 1 (4.3) | |
| Moderate | 29 (52.7) | 12 (52.2) | |
| Poorly | 25 (45.5) | 8 (34.8) | |
| Other | 0 | 2 (8.7) | |
| Post-op chemotherapy | 0.254 | ||
| No | 21 (38.2) | 12 (52.2) | |
| Yes | 34 (61.8) | 11 (47.8) | |
| Post-op radiotherapy | 0.266 | ||
| No | 46 (83.6) | 22 (95.7) | |
| Yes | 9 (16.4) | 1 (4.3) |