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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Xenobiotica. 2013 Sep 6;44(4):309–319. doi: 10.3109/00498254.2013.835885

Figure 4.

Figure 4

Michaelis-Menten Analysis of CYP2D6 Metabolism of Metoclopramide. CYP2D6 Supersomes were used to determine Km and vmax values for CYP2D6 metabolism of metoclopramide to deethylated metoclopramide. Km was 1.20 ± 0.29 μM and vmax was 6.1 ± 0.23 pmol product/min/pmol CYP2D6 with R2 value of 0.95 for the analysis.