Table 1.
Subject and CEEG monitoring characteristics by center (N=550).
| Center | Days for 50 Subjects |
Age in months median (IQR) |
Sex (male) N (%) |
Clinical seizure prior to CEEG N (%) |
Prior developmental delay or intellectual disability N (%) |
Prior Epilepsy N (%) |
CEEG >24 hours N (%) |
Seizure Occurrence by Acute Neurologic Diagnosis Category N with seizures / N in category (%) |
CEEG Monitoring Indication ** N (%) |
Mortality N (%) |
||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acute Structural |
Acute Non- Structural |
Epilepsy- Related |
Encephalopathy | Event | RSE Management |
|||||||||
| 1 | 920 | 44.5 (15,134) | 27 (54%)* | 41 (82%) | 35 (70%) | 30 (60%) | 25 (50%) | 1/5 (20%) | 3/12 (25%) | 17/33 (52%) | 11 (22%) | 38 (76%) | 13 (26%) | 2 (4%) |
| 2 | 52 | 24 (3, 144) | 28 (56%) | 23 (46%) | 19 (38%) | 9 (18%) | 5 (10%) | 1/20 (5%) | 4/22 (18%) | 3/8 (38%) | 18 (36%) | 18 (36%) | 6 (12%) | 6 (12%) |
| 3 | 496 | 36 (11,113) | 29 (58%) | 33 (66%) | 30 (60%) | 19 (38%) | 25 (50%) | 7/23 (30%) | 0/10 (0%) | 6/17 (35% | 39 (78%) | 21 (42%) | 6 (12%) | 3 (6%) |
| 4 | 416 | 28 (6,91) | 30 (60%) | 26 (52%) | 24 (48%) | 15 (30%) | 18 (38%) | 7/21 (33%) | 3/17 (18%) | 7/12 (58%) | 41 (82%) | 17 (34%) | 1(2%) | 13 (26%) |
| 5 | 769 | 56.2 (9,147) | 24 (48%) | 32 (64%) | 25 (50%) | 20 (40%) | 34 (68%) | 4/25 (16%) | 3/13 (23%) | 9/12 (75%) | 47 (94%) | 13 (26%) | 2 (4%) | 10 (20%) |
| 6 | 148 | 57.5 (11.5,138.5) | 33 (66%) | 20 (40%) | 14 (28%) | 15 (30%) | 19 (38%) | 3/28 (11%) | 2/10 (20%) | 8/12 (67%) | 30 (60%) | 16 (32%) | 10 (20%) | 2 (4%) |
| 7 | 293 | 31 (9.5,82) | 25 (50%) | 26 (52%) | 15 (30%) | 12 (24%) | 36 (72%) | 10/30 (33%) | 3/8 (38%) | 3/12 (25%) | 50 (100%) | 17 (34%) | 1 (2%) | 12 (24%) |
| 8 | 146 | 23 (5,110) | 29 (58%) | 19 (38%) | 12 (24%) | 11 (22%) | 36 (72%) | 9/32 (28%) | 0/3 (0%) | 7/15 (47%) | 38 (76%) | 7 (14%) | 4 (8%) | 10 (20%) |
| 9 | 239 | 61.7 (13.8,149.6) | 17 (34%) | 38 (76%) | 15 (30%) | 11 (22%) | 30 (60%) | 5/26 (19%) | 2/13 (15%) | 5/11 (45%) | 41 (82%) | 27 (54%) | 7 (14%) | 10 (20%) |
| 10 | 694 | 30.5 (11,102) | 30 (60%) | 27 (54%) | 16 (32%) | 14 (28%) | 21 (42%) | 4/16 (25%) | 3/16 (19%) | 8/18 (44%) | 39 (78%) | 9 (18%) | 2 (4%) | 3 (6%) |
| 11 | 635 | 25.5 (9,109) | 23 (46%) | 20(40%) | 22 (44%) | 18 (38%) | 18 (38%) | 7/19 (37%) | 0/17 (0%) | 8/14 (57%) | 14 (28%) | 26 (52%) | 10 (20%) | 2 (4%) |
| Overall N (%) |
Median (IQR) 416 (194-665) |
Median (IQR) 36.5 (9-122) |
295 (54%) | 305 (55%) | 227 (41%) | 174 (32%) | 267 (49%) | 58/245 (24%) | 23/141 (16%) | 81/164 (49%) | 386 (67%) | 209 (38%) | 62 (11%) | 72 (13%) |
| p-value | 0.41 | 0.1 | <0.001 | <0.001 | 0.005 | <0.001 | <0.001*** | <0.001 | <0.001 | <0.001 | <0.001 | |||
| 0.22 | 0.46 | 0.41 | ||||||||||||
Notes:
*
Cells values represent the number of subjects. For example, 27 of 50 subjects (54%) from Center 1 were male.
**
Subjects could have multiple CEEG monitoring indications.
***
There was a significant difference in seizure occurrence by acute neurologic diagnosis category (p<0.001) but within each acute neurologic diagnosis category there was no significant difference in seizure occurrence by center (Acute Structural p=0.22, Acute Non-Structural p=0.46, Epilepsy-Related p=0.41).