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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 2004 Apr 15;101(18):7205. doi: 10.1073/pnas.0401411101
PMCID: PMC406490

NEUROSCIENCE. For the article “The human olfactory receptor gene family,” by Bettina Malnic, Paul A. Godfrey, and Linda B. Buck, which appeared in issue 8, February 24, 2004, of Proc. Natl. Acad. Sci. USA (101, 2584–2589; first published February 13, 2004; 10.1073/pnas.0307882100), the authors note that the M71 receptor in Table 4 incorrectly recognizes the odorant heptanol and its perceived odor as “violet/woody.” Instead, the M71 receptor should recognize acetophenone, which has a “floral/woody” odor. The corrected table appears below.

Table 4. Potential associations between OR gene loci and odorant recognition.

Locus OR (MOR#)* Amino acid identity, % Odorant(s) recognized Perceived odor
1q22 OR23(267—13) 87 Lyral Lemony, green
5q35.3 IG7(276—1) 83 Limonene Lemon
9q34.11 ID3(136—6) 71 I-carvone Spearmint, caraway
11q12.1 OR73(174—9) 82 Eugenol Spicy
11q12.1 OR74(174—4) 76 Ethyl vanillin Vanilla
11q12.2 OR912—93(175—1) 66 2-Heptanone Fruity
11p15.4 S25(204—32) 74 n-aliphatic alcohols Herbal, woody, orange, rose
11p15.4 S46(32—4) 69 n-aliphatic acids Rancid, sour, sweaty, fatty
11p15.4 S85(13—6) 60 n-aliphatic acids As above
11p15.4 S86(8—2) 67 n-aliphatic acids As above
11p15.4 S18(31—2) 70 n-aliphatic acids/alcohols As above
11p15.4 S19(33—1) 62 n-aliphatic acids/alcohols As above
11p15.4 S41(22—2) 81 n-aliphatic acids/alcohols As above
11p15.4 S51(40—1) 83 n-aliphatic acids/alcohols As above
11p15.4 S83(40—4) 81 n-aliphatic acids/alcohols As above
11p15.4 I7(103—15) 87 n-aliphatic aldehydes Fatty
11q24.2 M71(171—2) 62 Acetophenone Floral/woody
14q11.1 S3(106—13P) 81 n-aliphatic alcohols Herbal, woody, orange, rose
14q11.1 S1(106—1) 87 n-aliphatic acids Rancid, sour, sweaty, fatty
17p13.3 hOR17—4 87 Bourgeonal Lily of the valley
17p13.3 hOR17—40 81 Helional Sweet, hay-like
*

Mouse OR designation according to ref. 7

OR73 and OR74 are in the same subfamily as are S1 and S3


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