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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2013 Aug;22(8):1476–1478. doi: 10.1158/1055-9965.EPI-13-0457

Correction: Reproductive, Lifestyle, and Anthropometric Risk Factors for Cancer in Elderly Women

PMCID: PMC4084685  NIHMSID: NIHMS486203

In this article (Cancer Epidemiol Biomarkers Prev 2013;22:681-687) which was published in the April 2013 issue of Cancer Epidemiology, Biomarkers & Prevention (1), the column in Table 2 with the number of samples for the ≥75 year age group was erroneously moved into the p-value column for the <75 year age group and all subsequent columns were shifted to the left due to a production error. The correct version of the table appears below. The publisher regrets the error.

Table 2.

Potential risk factors for ovarian, colon, rectal and breast cancers by age band at diagnosisa

< 75 years old ≥ 75 years old p for
interactionc

Cases Person-
years
HR (95%CI)b p or ptrend Cases Person-
years
HR (95%CI) b p or ptrend
Ovarian Cancer
Age at baseline
 < 60 92 159,819 1.0 21 43,137 1.0
 60 – 64 58 119,523 0.87 (0.61 – 1.25) 46 78,298 1.31 (0.75 – 2.27)
 ≥ 65 37 62,017 1.20 (0.77 – 1.87) 0.64 68 93,486 1.68 (0.98 – 2.88) 0.047 0.30
Physical activity level
 Low 71 159,835 1.0 57 42,905 1.0
 Moderate 53 91,546 1.27 (0.88 – 1.83) 44 88,953 1.23 (0.82 – 1.85)
 High 58 83,840 1.55 (1.08 – 2.22) 0.02 30 83,063 0.97 (0.62 – 1.53) 0.97 0.12
Family history of ovarian
cancerd
 No 173 332,244 1.0 132 209,471 1.0
 Yes 14 9,118 3.16 (1.83 – 5.45) <0.0001 3 5,450 0.93 (0.30 – 2.93) 0.90 0.06
Number of live births
 0 23 27,255 1.0 13 19,697 1.0
 1 – 2 59 101,834 0.69 (0.42 – 1.13) 41 70,019 0.91 (0.48 – 1.74)
 3 – 4 74 138,568 0.60 (0.37 – 0.96) 59 83,250 1.13 (0.60 – 2.11)
 5+ 31 71,782 0.45 (0.25 – 0.79) 0.005 21 40,477 0.85 (0.41 – 1.74) 0.98 0.09
Colon Cancer
Age at baseline
 <60 236 201,656 1.0 109 56,755 1.0
 60 – 64 228 147,680 1.57 (1.29 – 1.92) 281 99,470 1.29 (1.02 – 1.64)
 ≥65 140 74,351 2.28 (1.78 – 2.92) <0.0001 317 115,039 1.26 (0.99 – 1.60) 0.14 0.0002
Body mass index (BMI)
 <25 198 167,647 1.0 244 106,267 1.0
 25 - <30 235 156,583 1.28 (1.06 – 1.56) 274 103,759 1.18 (0.99 – 1.41)
 ≥30 171 99,157 1.44 (1.16 – 1.78) 0.0006 189 61,237 1.38 (1.13 – 1.69) 0.001 0.69
Smoking
 Never 370 274,486 1.0 495 191,764 1.0
 Past 130 80,119 1.27 (1.04 – 1.56) 115 47,178 0.97 (0.79 – 119)
 Current 96 62,381 1.27 (1.01 – 1.60) 0.01 79 27,915 1.22 (0.96 – 1.56) 0.22 0.53
Estrogen use
 Never 419 262,588 1.0 454 166,168 1.0
 Ever 185 160,799 0.71 (0.60 – 0.85) 0.0002 253 105,196 0.88 (0.75 – 1.03) 0.11 0.10
History of diabetes
 No 553 399,956 1.0 655 258,939 1.0
 Yes 51 22,877 1.35 (0.99 – 1.84) 0.06 51 11,928 1.59 (1.18 – 2.14) 0.002 0.54
Aspirin or NSAID usee
 No 100 60,565 1.0 125 40,488 1.0
 Yes 320 288,148 0.70 (0.56 – 0.89) 0.003 460 188,029 0.78 (0.64 – 0.95) 0.02 0.45
Rectal Cancer
Age at baseline
 <60 73 202,603 1.0 23 57,570 1.0
 60 – 64 65 147,866 1.40 (0.97 – 2.01) 48 101,157 1.11 (0.66 – 1.89)
 ≥65 45 74,575 2.34 (1.51 – 3.63) 0.0002 61 117,037 1.18 (0.69 – 2.00) 0.56 0.05
Smoking
 Never 105 275,540 1.0 90 194,832 1.0
 Past 38 80,560 1.23 (0.84 – 1.80) 26 48,062 1.23 (0.80 – 1.91)
 Current 35 62,541 1.68 (1.13 – 2.49) 0.01 14 28,401 1.19 (0.67 – 2.11) 0.36 0.54
Estrogen use
 Never 129 263,669 1.0 87 169,110 1.0
 Ever 54 161,375 0.70 (0.50 – 0.96) 0.03 45 106,654 1.00 (0.67 – 1.48) 1.00 0.37
Oral contraceptive use
 No 140 332,079 1.0 122 234,829 1.0
 Yes 43 92,964 1.27 (0.88 – 1.83) 0.20 10 40,935 0.46 (0.23 – 0.91) 0.03 0.04
Breast Cancer
Age at baseline
 < 60 687 196,272 1.0 207 53,319 1.0
 60 – 64 613 143,414 1.35 (1.19 – 1.52) 414 93,515 1.10 (0.92 – 1.32)
 ≥ 65 293 72,946 1.35 (1.15 – 1.58) <0.0001 450 110,055 1.07 (0.89 – 1.29) 0.59 0.006
Body mass index (BMI)
 < 25 547 163,218 1.0 353 100,980 1.0
 25 - < 30 606 152,625 1.18 (1.04 – 1.33) 449 98,029 1.30 (1.12 – 1.52) 0.0006
 ≥ 30 440 96,579 1.35 (1.17 – 1.55) <0.0001 269 57,880 1.35 (1.13 – 1.62) 0.001 0.80
Waist-hip-ratio (WHR)
 Q1 (0.335 – 0.777) 383 110,216 1.0 246 63,163 1.0
 Q2 (>0.777 – 0.832) 367 104,033 0.97 (0.83 – 1.12) 258 65,248 0.99 (0.82 – 1.18)
 Q3 (>0.832 – 0.892) 388 100,772 1.01 (0.87 – 1.18) 271 65,577 0.99 (0.82 – 1.19)
 Q4 (>0.892 – 2.836) 448 95,813 1.18 (1.01 – 1.38) 0.02 290 61,990 1.05 (0.87 – 1.28) 0.63 0.26
Family history of breast
cancerd
 No 1,138 318,733 1.0 732 198,514 1.0
 Yes 455 93,899 1.35 (1.21 – 1.51) <0.0001 339 58,374 1.57 (1.37 – 1.79) <0.0001 0.09
Age at menarche
 ≤ 12 725 175,292 1.0 432 105,074 1.0
 > 12 855 232,907 0.90 (0.81 – 1.00) 0.048 631 148,502 1.06 (0.94 – 1.21) 0.34 0.05
Age at menopause
 < 50 778 215,226 1.0 463 130,677 1.0
 ≥ 50 815 197,407 1.15 (1.04 – 1.27) 0.008 608 126,211 1.35 (1.19 – 1.53) <0.0001 0.04
Number of live births
 0 160 36,201 1.0 107 25,838 1.0
 1 – 2 511 125,740 0.57 (0.39 – 0.84) 384 84,903 0.70 (0.44 – 1.11)
 3 – 4 660 166,743 0.58 (0.41 – 0.82) 409 98,813 0.64 (0.42 – 0.98)
 5+ 262 83,948 0.45 (0.32 – 0.65) <0.0001 171 47,335 0.57 (0.37 – 0.88) 0.001 0.50
Age at first live birth
 < 20 285 86,040 1.0 159 44,593 1.0
 20 – 24 723 193,329 1.12 (0.98 – 1.29) 463 112,881 1.18 (0.98 – 1.42)
 25 – 29 308 74,508 1.17 (0.99 – 1.39) 247 55,451 1.18 (0.95 – 1.46)
 ≥ 30 108 20,329 1.45 (1.14 – 1.83) 0.003 89 16,613 1.40 (1.06 – 1.85) 0.03 0.43
 Nulliparous 160 36,201 1.06 (0.84 – 1.34) 107 25,838 1.05 (0.78 – 1.42)
Smoking
 Never 998 267,781 1.0 744 181,870 1.0
 Past 313 78,153 1.06 (0.93 – 1.21) 209 44,314 1.17 (1.00 – 1.38)
 Current 265 60,483 1.25 (1.08 – 1.44) 0.004 100 26,458 0.99 (0.80 – 1.24) 0.43 0.22
Alcohol consumption
 No 832 228,828 1.0 631 149,329 1.0
 Yes 761 183,805 1.20 (1.08 – 1.33) 0.0007 440 107,559 0.98 (0.86 – 1.11) 0.73 0.02
History of hysterectomy
 No 1,088 276,458 1.0 703 174,329 1.0
 Yes 505 136,174 1.02 (0.91 – 1.16) 0.71 368 82,530 1.31 (1.13 – 1.51) 0.0003 0.03
Aspirin or NSAID usee
 No 256 56,990 1.0 159 36,932 1.0
 Yes 1,040 280,606 0.82 (0.71 – 0.94) 0.005 737 177,556 0.94 (0.78 – 1.12) 0.46 0.28
a

Includes only risk factors where the association was significant in at least one of the risk sets. All remaining risk factors are included in the supplementary tables.

b

Adjusted for age at baseline, BMI (kg/m2), physical activity level (low, moderate, high), smoking (never, past, current), age at menarche (ovarian, breast), estrogen use (colon, rectal), WHR (breast), age at menopause (breast), number of live births (breast), age at first live births (breast) and alcohol intake (breast).

c

P values for tests whether HRs differ by the follow-up (< 75 y.o. vs ≥ 75 y.o.)

d

Family history among first and second degree relatives.

e

Analysis was restricted to women who were alive and responded to the follow-up 3 (1992) questionnaire.

Reference

  • 1.Poynter JN, Inoue-Choi M, Ross JA, Jacobs DR, Jr, Robien K. Reproductive, Lifestyle, and Anthropometric Risk Factors for Cancer in Elderly Women. Cancer Epidemiol Biomarkers Prev. 2013;22:681–687. doi: 10.1158/1055-9965.EPI-12-0966. [DOI] [PMC free article] [PubMed] [Google Scholar]

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