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. 2014 Jun 20;6(2):333–353. doi: 10.3390/pharmaceutics6020333

Table 4.

Examples of aerosolized PEGylated nanocarrier delivery to the lungs.

Aerosol Type PEG Length Therapeutic Carrier Disease Reference
DPI 2, 3, and 5 kDa Paclitaxel PEG Lung cancer [62]
DPI 5 kDa Curcumin PLGA–PEG chitosan Asthma, COPD, Cystic Fibrosis [85]
DPI 8 kDa Ciprofloxacin PEG Respiratory infections [81]
Colloidal Dispersion 2 kDa Ciprofloxacin PEGylated liposome Respiratory infections [34]
DPI Insulin PEG Diabetes mellitus [87]

Abbreviations: COPD, chronic obstructive pulmonary disease; DPI, dry powder inhaler; PLGA, poly(lactic-co-glycolic acid).