Table 3. Comparison of tPA treatment groups.

tPA - Recombinant Tissue Plasminogen Activator, TIA - Transient Ischemic Attack, sICH - Symptomatic intracerebral hemorrhage, NIHSS - National Institutes of Health Stroke Scale, CEA - Carotid Endarterectomy, NASCET - North American Symptomatic Carotid Endarterectomy Trial

			Treated with tPA (n = 11)	Not treated with tPA (n = 131)	P
Age (years)			68 (53–72)	66 (58–75)	0.8
Gender	Female		4	59	0.3
Comorbidities	Hypertension		9	89	0.5
	Hyperlipidemia		6	57	0.5
	Diabetes Mellitus		3	36	1.0
	Cardiac Disease		2	49	0.3
Smoking History			8	78	0.3
Clinical Presentation	Stroke TIA		11 0	70 61	0.002
Baseline NIHSS+			9 (2–17)*	4 (1–9)*	0.2
Anticoagulant Therapy	At presentation		3	25	0.7
	Before CEA		7	38	0.2
	After CEA		9	86	0.5
Antiplatelet Therapy	At presentation		10	90	1.0
sICH after CEA			2	1	0.02
Stenosis Grade (%)	>70%		9	112	0.6
Symptom to CEA Interval (days)			22 (2–49)*	14 (6–61)*	0.46
Abnormal Platelet Count			1	8	0.5
Mean Arterial Pressure	At admission		101	104	0.5
	First 48 hours after admission	Mean Maximum	93 114	97 110	0.3 0.3
	Immediately before CEA		95	97	0.7
	Intraoperative	Mean Maximum	93 116	97 115	0.2 0.8
	First 48 hours after CEA#	Mean Maximum	88 110	87 105	0.7 0.06

^*Median (Interquartile Range)

⁺Patients with ischemic stroke

^#Until onset of hemorrhage in patients who developed sICH