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100 nm GLP-1/Glb 11 potentiates insulin secretion. 20 mm glucose causes a ~4 fold induction in insulin secretion in INS 832/3 cells. At non-stimulatory glucose, GLP-1/Glb 11 had no significant effect on basal secretion. However, GLP-1/Glb 11 substantially potentiates glucose stimulated insulin secretion in the INS 832/3 cell line by ~6 fold ( #= p<0.05 between 1 mm glucose and 20 mm glucose and $= p<0.05 between 20 mm glucose and 20 mm glucose + 100 nm GLP-1/Glb).
