Table 1.
Path a: Regions correlated with stimulation temperature.1
| Brain Region (Brodmann Areas) | Coordinates (mm) | # of voxels p<.001 | Volume (mm) | Max Z-score | Mean Path a coeff. (std. err) | Mean p-value Path a | ||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| x | y | z | ||||||
| Temperature-related increases | ||||||||
| Bilateral cerebellum | -14 | -66 | -34 | 6081 | 48648 | 15.13 | 0.9010 (0.17) | 0.0000 |
| Right temporal pole | 48 | -22 | -36 | 6 | 48 | 5.86 | 0.0774 (0.03) | 0.0026 |
| Right insula, contiguous with bilateral thalamus, midbrain, right inferior frontal gyrus, right lateral PFC, right premotor cortex, right lateral OFC, right hippocampus | 36 | 2 | 8 | 12180 | 97440 | 17.22 | 0.9217 (0.12) | 0.0001 |
| Right Inferior Frontal Gyrus p. Orbitalis, contiguous with right anterior insula and right VLPFC | 26 | 14 | -24 | 12 | 96 | 5.45 | 0.4488 (0.17) | 0.0087 |
| Left Middle Orbital Gyrus | -26 | 38 | -20 | 84 | 672 | 11.18 | 0.6833 (0.18) | 0.0002 |
| Left Middle Orbital Gyrus | -22 | 58 | -16 | 38 | 304 | 6.26 | 0.8102 (0.34) | 0.0050 |
| Right Middle Temporal Gyrus | 58 | -40 | -10 | 43 | 344 | 8.87 | 0.4104 (0.12) | 0.0006 |
| Left Rolandic Operculum | -46 | -4 | 10 | 3654 | 29232 | 13.63 | 0.8228 (0.10) | 0.0002 |
| Left Calcarine Gyrus (BA17) | 2 | -84 | 0 | 416 | 3328 | 10.26 | 0.9811 (0.25) | 0.0003 |
| Right Calcarine Gyrus (BA17) | 16 | -102 | -4 | 18 | 144 | 5.9 | 0.3819 (0.15) | 0.0043 |
| Cerebellar Vermis 4/5 | 2 | -46 | -2 | 106 | 848 | 13.82 | 1.2624 (0.42) | 0.0000 |
| Left Insula Lobe (OP2) | -38 | -18 | 14 | 54 | 432 | 12.09 | 0.4722 (0.13) | 0.0001 |
| Right Middle Cingulate Cortex (BA6) | 6 | 6 | 44 | 5699 | 45592 | 19.94 | 0.8975 (0.12) | 0.0002 |
| Left Middle Frontal Gyrus | -38 | 42 | 28 | 320 | 2560 | 10.1 | 0.7566 (0.17) | 0.0016 |
| Right Middle Frontal Gyrus | 38 | 50 | 28 | 18 | 144 | 5.62 | 0.8758 (0.30) | 0.0037 |
| Left caudal cingulate | -18 | -28 | 34 | 55 | 440 | 8.06 | 0.4528 (0.13) | 0.0003 |
| Left Inferior Parietal Lobule (hIP2) | -44 | -42 | 36 | 6 | 48 | 6.27 | 0.3704 (0.15) | 0.0019 |
| Left Precuneus | -6 | -80 | 54 | 4 | 32 | 5.21 | 0.5817 (0.25) | 0.0100 |
| Left Superior Frontal Gyrus (BA6) | -18 | 4 | 66 | 238 | 1904 | 12.39 | 0.2750 (0.07) | 0.0000 |
| Right Superior Parietal Lobule | 24 | -46 | 70 | 367 | 2936 | 13.42 | 0.2867 (0.07) | 0.0001 |
| Temperature-related decreases | ||||||||
| Right Medial Temporal Pole | 44 | 12 | -42 | 30 | 240 | 6.62 | -0.5364 (0.18) | 0.0006 |
| Left hippocampus, contiguous with parahippocampal gyrus left medial temporal lobe, left occipital cortex | -34 | -54 | -8 | 7155 | 57240 | 10.95 | -0.7752 (0.10) | 0.0006 |
| Right hippocampus, contiguous with parahippocampal gyrus and right occipital cortex | 40 | -64 | 2 | 5973 | 47784 | 11.59 | -0.8269 (0.14) | 0.0005 |
| Right Medial Temporal Pole | 54 | 14 | -32 | 2 | 16 | 4.87 | -0.6793 (0.27) | 0.0084 |
| Right Middle Temporal Gyrus | 58 | -8 | -16 | 429 | 3432 | 10.36 | -0.9178 (0.21) | 0.0001 |
| Right amygdala | 14 | 2 | -28 | 4 | 32 | 5.71 | -0.4142 (0.14) | 0.0016 |
| Left Rectal Gyrus | -6 | 14 | -24 | 22 | 176 | 7.02 | -0.3120 (0.09) | 0.0005 |
| Right Inferior Temporal Gyrus | 66 | -24 | -26 | 3 | 24 | 5.02 | -0.1715 (0.06) | 0.0033 |
| Left Superior Medial Gyrus | -4 | 54 | 4 | 1634 | 13072 | 9.44 | -0.9172 (0.20) | 0.0047 |
| Left Rectal Gyrus | -8 | 24 | -14 | 11 | 88 | 5.86 | -0.4067 (0.14) | 0.0034 |
| Right Cerebelum IV-V | 10 | -56 | -12 | 4 | 32 | 4.86 | -0.5879 (0.22) | 0.0075 |
| Left Inferior Frontal Gyrus p. Orbitalis | -54 | 24 | -4 | 42 | 336 | 6.96 | -0.7147 (0.23) | 0.0013 |
| Right Precuneus | 2 | -44 | 44 | 2458 | 19664 | 11.26 | -0.7598 (0.13) | 0.0001 |
| Left Superior Frontal Gyrus | -18 | 62 | 2 | 6 | 48 | 5.28 | -0.4488 (0.17) | 0.0078 |
| Right Superior Temporal Gyrus | 44 | -28 | 4 | 33 | 264 | 7.57 | -0.3953 (0.11) | 0.0002 |
| Right Calcarine Gyrus (BA18) | 22 | -58 | 8 | 13 | 104 | 6.52 | -0.6114 (0.21) | 0.0052 |
| RightPrecentral Gyrus (BA1) | 52 | -14 | 46 | 1377 | 11016 | 10.94 | -0.7646 (0.15) | 0.0004 |
| Left Postcentral Gyrus (BA3b) | -40 | -32 | 52 | 3869 | 30952 | 11.1 | -0.7422 (0.13) | 0.0014 |
| Right Superior Frontal Gyrus | 22 | 36 | 38 | 350 | 2800 | 9.41 | -0.5574 (0.13) | 0.0003 |
| Left Middle Frontal Gyrus | -40 | 10 | 50 | 122 | 976 | 7.41 | -0.5397 (0.16) | 0.0011 |
| Left Middle Frontal Gyrus | -26 | 24 | 46 | 138 | 1104 | 8.49 | -0.8461 (0.25) | 0.0009 |