Table 3. Least Square Mean Estimates of Three PANSS Ratings by Genotype Groups in the European Ancestry Sample of CATIE Study.

Genotype	General psychopathology				Negative PANSS				Positive
	Estimate	SE	p	p*	Estimate	SE	p	p*	Estimate	SE	p	p*
rs17041184a
TT	2.5426	0.477	<0.0001	0.6116	0.944	0.3135	0.0028	0.3621	1.4958	0.3056	<0.0001	0.5685
CT+CC	1.8205	1.3385	0.1745		1.797	0.8808	0.042		0.9758	0.8582	0.2562
rs10490162
AA	2.1518	0.501	<0.0001	0.1835	0.8123	0.3276	0.0136	0.0888	1.2985	0.32	<0.0001	0.3871
AG+GG	3.6357	0.9947	0.0003		2.0560	0.6513	0.0017		1.9148	0.636	0.0028

Note: p, p value for treatment effect in each genotype group from the post-hoc analysis based on general linear mixed model; p*, p value for genotype and treatment interaction to test whether or not antipsychotic response was different by genotype group.

^ars17041184 is a proxy SNP of rs12467557 (r²=1 and D'=1), which was not genotyped in CATIE data.