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. 2014 Jul 11;142(4):573–580. doi: 10.1111/imm.12263

Figure 1.

Figure 1

Increased interleukin-21 (IL-21) in sera and CD4+ T cells of patients with systemic lupus erythematosus (SLE). (a) The concentrations of IL-21 in sera isolated from 22 SLE patients and 16 healthy controls were analysed by ELISA. (b) Peripheral blood mononuclear cells (PBMCs) and CD4+ T cells were isolated from heparinized peripheral blood obtained from three patients and three healthy controls. The mRNA expression levels of IL-21 and IL-21 receptor were determined by RT-PCR. Results are expressed as means ± standard deviation (SD). (**P < 0·001).