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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1978 Feb;75(2):586–587. doi: 10.1073/pnas.75.2.586

Adaptive design in regression and control

T L Lai 1, Herbert Robbins 1
PMCID: PMC411301  PMID: 16592494

Abstract

When y = M(x) + ε, where M may be nonlinear, adaptive regression designs of the levels x1, x2,... at which y1, y2,... are observed lead to asymptotically efficient estimates of the value θ of x for which M(θ) is equal to any desired value y*. More importantly, these designs also make the “cost” of the observations, defined at the nth stage to be Σ1n (xi — θ)2, to be of the order of log n instead of n, an obvious advantage in medical and other applications.

Keywords: iterated least squares, adaptive stochastic approximation, nonlinear regression, control theory, optimal dosage estimation

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Lai T. L., Robbins H. Strong consistency of least-squares estimates in regression models. Proc Natl Acad Sci U S A. 1977 Jul;74(7):2667–2669. doi: 10.1073/pnas.74.7.2667. [DOI] [PMC free article] [PubMed] [Google Scholar]

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