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. 1978 Mar;75(3):1247–1249. doi: 10.1073/pnas.75.3.1247

Defective regulation of cholesterol biosynthesis and plasma membrane fluidity in a Chinese hamster ovary cell mutant.

M Sinensky
PMCID: PMC411447  PMID: 274716

Abstract

A Chinese hamster ovary cell mutant resistant to killing by 25-hydroxycholesterol is shown to be defective in the regulation of cholesterol synthesis by exogenous cholesterol. When grown with various cholesterol supplements in delipidized serum, the mutant cell exhibits a variation in cholesterol content and plasma membrane fluidity that is not observed in the parental cell type.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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