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. 1979 Sep;76(9):4658–4660. doi: 10.1073/pnas.76.9.4658

Sodium transport inhibitor from bovine hypothalamus.

G T Haupert Jr, J M Sancho
PMCID: PMC411639  PMID: 228304

Abstract

A low molecular weight, basic, nonpeptidic factor that possesses sodium transport inhibitory properties has been prepared from bovine hypothalamus by acid/acetone extraction and gel filtration. Concentration and partial purification was achieved by ion-exchange chromatography. This substance inhibits active Na+ transport across anuran membranes, inhibits ouabain binding to frog urinary bladder, and directly inhibits renal Na+,K+-ATPase. This substance thus possesses the putative characteristics of a natriuretic factor of hypothalamic origin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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