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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Circulation. 2006 Sep 4;114(11):1159–1168. doi: 10.1161/CIRCULATIONAHA.106.637124

Figure 5.

Figure 5

Foxo1 and Foxo3 are inactivated in load-induced hypertrophy. A, Protein extracts from sham-operated or TAB LVs 3 weeks after surgery were separated by SDS-PAGE and probed with antibodies against phosphorylated or total Foxo1 and Foxo3. B, Mean values of phosphorylated Foxo/total Foxo ratios from sham- or TAB-treated groups were normalized to the mean value of the phosphorylated Foxo/total Foxo from the sham group (n=4 to 5). C, Time course of Foxo phosphorylation in hypertrophic hearts. LV protein extracts from sham-operated (S) or TAB (T) mice were probed with antibodies against phosphorylated or total Foxo protein. *P≤0.05, **P≤0.01 vs sham group.