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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1979 Oct;76(10):5336–5339. doi: 10.1073/pnas.76.10.5336

Ultrasensitive enzymatic radioimmunoassay: application to detection of cholera toxin and rotavirus.

C C Harris, R H Yolken, H Krokan, I C Hsu
PMCID: PMC413137  PMID: 228285

Abstract

Rotavirus and enterotoxin-producing bacteria are major causes of diarrheal disease in humans. A method of rapid diagnosis, ultrasensitive enzymatic radioimmunoassay, has been developed to quantitatively detect cholera toxin and rotavirus. The method uses features of both enzyme-linked immunosorbent assay and radioimmunoassay; however, the sensitivity of the assay is 100- to 1000-fold more sensitive than the two parent assays. Ultrasensitive enzymatic radioimmunoassay should also be useful in measuring other biologically important agents such as drugs and hormones.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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