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. 2013 Nov 6;3(6):267–270. doi: 10.1007/s13659-013-0074-z

Cipatrijugin G, a new trijugin-type limonoid bearing an uncommon γ-hydroxybutenolide unit from the aerial parts of Cipadessa cinerascens

Cheng-Shi Jiang 1, Yan Li 1, Zhen-Zhong Wang 2, Xiao-Yin Huang 1, Wei Xiao 2,✉, Yue-Wei Guo 1,✉
PMCID: PMC4131602

Abstract

A new trijugin-type limonoid, cipatrijugin G (1), together with the related known cipatrijugin A (2), were isolated from the aerial parts of Cipadessa cinerascens. The structure of the new compound was determined by extensive analysis of its spectroscopic data and by comparison of its NMR data with those reported in the literature. Compound 1 showed cytotoxicity against tumor cell line A549 with an IC50 value of 9.78 μM. This is the first report of a trijugin-type limonoid bearing a γ-hydroxybutenolide unit, in comparison to the common furan unit as ring E. graphic file with name 13659_2013_74_Article_Fig1_HTML.jpg

Electronic Supplementary Material

Supplementary material is available for this article at 10.1007/s13659-013-0074-z and is accessible for authorized users.

Keywords: Cipadessa cinerascens, trijugin-type, limonoid

Electronic supplementary material

13659_2013_74_MOESM1_ESM.pdf (483.5KB, pdf)

Supplementary material, approximately 475 KB.

Footnotes

This article is published with open access at Springerlink.com

Contributor Information

Wei Xiao, Email: wzhzh-nj@163.net.

Yue-Wei Guo, Email: ywguo@mail.shcnc.ac.cn.

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13659_2013_74_MOESM1_ESM.pdf (483.5KB, pdf)

Supplementary material, approximately 475 KB.

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