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. 2012 Dec 20;2(6):249–254. doi: 10.1007/s13659-012-0082-4

Four new indole alkaloids from Plantago asiatica

Zhong-Hua Gao 1,2, Ling-Mei Kong 1, Xi-Sheng Zou 1, Yi-Ming Shi 1,2, Shan-Zhai Shang 1, Huai-Rong Luo 1, Cheng-Qin Liang 1, Xiao-Nian Li 1, Yan Li 1, Xue Du 1, Wei-Lie Xiao 1,✉, Han-Dong Sun 1,✉
PMCID: PMC4131610

Graphical abstract

Four new indole alkaloids, plasiaticines A-D (1–4), together with two known ones, were isolated from the seeds of Plantago asiatica. The structures of the new compounds were elucidated on the basis of comprehensive analysis of spectroscopic data. All compounds were tested for their cytotoxic activity, and all compounds except 4 were tested for their acetylcholinesterase (AChE) inhibitory activities.

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Electronic Supplementary Material

Supplementary material is available for this article at 10.1007/s13659-012-0082-4 and is accessible for authorized users.

Keywords: Plantago asiatica, indole alkaloid, AChE inhibitory activity, cytotoxic activity

Electronic supplementary material

13659_2012_82_MOESM1_ESM.pdf (3MB, pdf)

Supplementary material, approximately 3.01 MB.

Footnotes

This article is published with open access at Springerlink.com

Contributor Information

Wei-Lie Xiao, Email: xwl@mail.kib.ac.cn.

Han-Dong Sun, Email: hdsun@mail.kib.ac.cn.

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13659_2012_82_MOESM1_ESM.pdf (3MB, pdf)

Supplementary material, approximately 3.01 MB.

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