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. 2013 Apr 3;3(2):56–60. doi: 10.1007/s13659-013-0017-8

Four new lignans from the leaves and stems of Schisandra propinqua var. sinensis

Shan-Zhai Shang 117,317, Ying-Shan Han 217, Yi-Ming Shi 117,317, Xue Du 117, Cheng-Qin Liang 117,317, Mark A Wainberg 217, Zhong-Hua Gao 117,317, Wei-Lie Xiao 117,✉, Han-Dong Sun 117,✉
PMCID: PMC4131657

Abstract

Four new tetrahydrofuran lignans, schpropinrins A-D (1–4), together with five known ones, were isolated from the leaves and stems of Schisandra propinqua var. sinensis. Their structures, including absolute configurations, were characterized by means of spectroscopic analysis and ECD calculation. Compounds 1–4 featured a ketal or hemiketal substructure at C-7 and all of the isolates were tested for their anti-HIV integrase activity. graphic file with name 13659_2013_17_Article_Fig1_HTML.jpg

Electronic Supplementary Material

Supplementary material is available for this article at 10.1007/s13659-013-0017-8 and is accessible for authorized users.

Keywords: Schisandra propinqua var. sinensi, schpropinrins, lignan, anti-human immunodeficiency virus integrase activity

Electronic supplementary material

13659_2013_17_MOESM1_ESM.pdf (4.1MB, pdf)

Supplementary material, approximately 4.15 MB.

Footnotes

This article is published with open access at Springerlink.com

Contributor Information

Wei-Lie Xiao, Email: xwl@mail.kib.ac.cn.

Han-Dong Sun, Email: hdsun@mail.kib.ac.cn.

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Supplementary Materials

13659_2013_17_MOESM1_ESM.pdf (4.1MB, pdf)

Supplementary material, approximately 4.15 MB.

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