Abstract
Abietane diterpenes and miltirone series have shown important activities and for medical purposes in order to achieve the total synthesis of 1-oxomiltrone 1 and miltirone 4, a versatile intermediate 6 was found. The compound 6 could be used as a precursor A-B-C rings with different oxidative degrees in selected abietane diterpenes when synthesized through high yield Suzuki reaction and subsequent cyclization, and total synthesis of 1-oxomiltirone (1) has been achieved. 
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Keywords: total synthesis, Suzuki coupling, 1-oxomiltirone, abietane diterpenes, versatile intermediate
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Contributor Information
Tie-Jun Ling, Email: lingtj@ahau.edu.cn.
Hong-Bo Qin, Email: qinhongbo@mail.kib.ac.cn.
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Supplementary material, approximately 1.09 MB.