ent-Kaurane diterpenoids from the plant Wedelia trilobata

Bing-Ji Ma; Chun-Nan Wen; Yuan Gao; Fu-Cai Ren; Fei Wang; Ji-Kai Liu

doi:10.1007/s13659-013-0029-4

. 2013 Jun 1;3(3):107–111. doi: 10.1007/s13659-013-0029-4

ent-Kaurane diterpenoids from the plant Wedelia trilobata

Bing-Ji Ma ¹, Chun-Nan Wen ^1,², Yuan Gao ^2,³, Fu-Cai Ren ², Fei Wang ^2,³, Ji-Kai Liu ^3,^✉

PMCID: PMC4131666

Abstract

Four new ent-kaurane diterpenoids, namely, 3α-tigloyloxypterokaurene L₃ (1), ent-17-hydroxy-kaura-9(11),15-dien-19-oic acid (2), and wedelobatins A (3) and B (4), together with 11 known ent-kaurane diterpenoids (5-15), were isolated from the ethanol extract of Wedelia trilobata. All the structures of 1–15 were elucidated on the basis of spectroscopic studies. graphic file with name 13659_2013_29_Article_Fig1_HTML.jpg

Electronic Supplementary Material

Supplementary material is available for this article at 10.1007/s13659-013-0029-4 and is accessible for authorized users.

Keywords: ent-kaurane diterpenoids, Wedelia trilobata, phytochemical investigation

Electronic supplementary material

13659_2013_29_MOESM1_ESM.pdf^{(2.2MB, pdf)}

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This article is published with open access at Springerlink.com

References

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Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

13659_2013_29_MOESM1_ESM.pdf^{(2.2MB, pdf)}

Supplementary material, approximately 2.16 MB.

[CR1] [1].That Q T, Jossang J, Jossang A, Kim P P N, Jaureguiberry G. J. Org. Chem. 2007;72:7102–7105. doi: 10.1021/jo070771m. [DOI] [PubMed] [Google Scholar]

[CR2] [2].Balekar N, Nakpheng T, Katkam N G, Srichana T. Phytomedicine. 2012;19:1178–1184. doi: 10.1016/j.phymed.2012.07.014. [DOI] [PubMed] [Google Scholar]

[CR3] [3].Bohlmann F, Ziesche J, King R M, Robinson H. Phytochemistry. 1981;20:751–756. doi: 10.1016/0031-9422(81)85167-9. [DOI] [Google Scholar]

[CR4] [4].Vieira H S, Takahashi J A, Boaventura M A D. Fitoterapia. 2001;72:854–856. doi: 10.1016/S0367-326X(01)00332-X. [DOI] [PubMed] [Google Scholar]

[CR5] [5].Qiang Y, Du D L, Chen Y J, Gao K. Helv. Chim. Acta. 2011;94:817–823. doi: 10.1002/hlca.201000301. [DOI] [Google Scholar]

[CR6] [6].Roynolds W F, Enríquez R G, Escobar L I, Lozoya X. Can. J. Chem. 1984;62:2421–2425. doi: 10.1139/v84-416. [DOI] [Google Scholar]

[CR7] [7].Hutchison M, Lewer P, MacMillan J. J. Chem. Soc., Perkin Trans. 1. 1984;10:2363–2366. doi: 10.1039/p19840002363. [DOI] [Google Scholar]

[CR8] [8].Morris B D, Charlet L D, Foster S P. J. Chem. Ecol. 2009;35:50–57. doi: 10.1007/s10886-008-9567-3. [DOI] [PubMed] [Google Scholar]

[CR9] [9].Jung H A, Lee E J, Kim J S, Kang S S, Lee J H, Min B S, Choi J S. Arch. Pharm. Res. 2009;32:1399–1408. doi: 10.1007/s12272-009-2009-0. [DOI] [PubMed] [Google Scholar]

[CR10] [10].Ragasa C Y, Padolina W G, Bowden B F, Li S X, Tapiolas D M, Coll J C. J. Nat. Prod. 1993;56:386–393. doi: 10.1021/np50093a011. [DOI] [Google Scholar]

[CR11] [11].Ahmed M, Jakupovic J, Castro V. Phytochemistry. 1991;30:1712–1714. doi: 10.1016/0031-9422(91)84242-K. [DOI] [Google Scholar]

[CR12] [12].Silva E A, Takahashi J A, Boaventura M A D, Oliveira A B. Phytochemistry. 1999;52:397–400. doi: 10.1016/S0031-9422(99)00219-8. [DOI] [PubMed] [Google Scholar]

[CR13] [13].Li C, Lee D, Graf T N, Phifer S S, Nakanishi Y, Riswan S, Setyowati F M, Saribi A M, Soejarto D D, Farnsworth N R, Falkinham J O, III, Kroll D J, Kinghorn A D, Wani M C, Oberlies N H. J. Nat. Prod. 2009;72:1949–1953. doi: 10.1021/np900572g. [DOI] [PMC free article] [PubMed] [Google Scholar]

[CR14] [14].Santos, H. S.; Barros, F. W. A.; Albuquerque, M. R. J. R.; Bandeira, P. N.; Pessoa, C.; Braz-Filho, R.; Monte, F. J. Q.; Leal-Cardoso, J. H.; Lemos, T. L. G. J. Nat. Prod.2009, 72, 1884-1887. [DOI] [PubMed]

[CR15] [15].Cuenca M D R, Catalan C A N, Díaz J G, Herz W. J. Nat. Prod. 1991;54:1162–1164. doi: 10.1021/np50076a047. [DOI] [Google Scholar]

[CR16] [16].Wu M L, Zhang D Z, Xu Q J, Xie R R, Li Q Q. Zhongcaoyao. 2010;41:681–685. [Google Scholar]

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ent-Kaurane diterpenoids from the plant Wedelia trilobata

Bing-Ji Ma

Chun-Nan Wen

Yuan Gao

Fu-Cai Ren

Fei Wang

Ji-Kai Liu

Abstract

Electronic Supplementary Material

Electronic supplementary material

Footnotes

References

Associated Data

Supplementary Materials

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ent-Kaurane diterpenoids from the plant Wedelia trilobata

Bing-Ji Ma

Chun-Nan Wen

Yuan Gao

Fu-Cai Ren

Fei Wang

Ji-Kai Liu

Abstract

Electronic Supplementary Material

Electronic supplementary material

Footnotes

References

Associated Data

Supplementary Materials

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