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. 2011 Sep 2;1(1):33–36. doi: 10.1007/s13659-011-0008-6

Three new nortriterpenoids from Schisandra wilsoniana and their anti-HIV-1 activities

Guang-Yu Yang 1,2, Yin-Ke Li 3, Xing-Jie Zhang 4, Xiao-Nian Li 1, Liu-Meng Yang 4, Yi-Ming Shi 1, Wei-Lie Xiao 1,✉, Yong-Tang Zheng 4, Han-Dong Sun 1,✉
PMCID: PMC4131707

Abstract

Three new highly oxygenated nortriterpenoids, wilsonianadilactones D–F (1–3), were isolated from the leaves and stems of Schisandra wilsoniana. Their structures were established by means of spectroscopic analysis. Compounds 1–3 showed weak anti-HIV-1 activity with the therapeutic index (TI) values (CC50/EC50) greater than 8.16, 14.7, and 17.5, respectively. Inline graphic

Keywords: nortriterpenoid, wilsonianadilactone, Schisandra wilsoniana

Footnotes

This article is published with open access at Springerlink.com

Contributor Information

Wei-Lie Xiao, Email: xwl@mail.kib.ac.cn.

Han-Dong Sun, Email: hdsun@mail.kib.ac.cn.

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