Table 3.
Predictor variables | Model 11
|
Model 22
|
Model 33
|
||||||
---|---|---|---|---|---|---|---|---|---|
β | SE | p | β | SE | p | β | SE | P | |
Baseline Cortisol | |||||||||
Intercept | .559 | .403 | .167 | .331 | .410 | .421 | .396 | .414 | .340 |
Time since feeding (min)4 | −.164 | .068 | .017 | −.169 | .068 | .013 | −.161 | .068 | .019 |
GA at birth (weeks)5 | −.012 | .051 | .808 | −.034 | .053 | .515 | −.039 | .053 | .463 |
Caffeine use6 | .396 | .150 | .009 | .235 | .148 | .114 | .302 | .158 | <.001 |
Infant age (hours)4 | −.155 | .044 | <.001 | −.160 | .044 | <.001 | −.158 | .044 | <.001 |
MSDP | −.223 | .123 | .071 | - | - | - | −.155 | .132 | .241 |
NR3C1 methylation CpG 3 | - | - | - | .105 | .046 | .024 | .089 | .048 | .064 |
NR3C1 methylation CpG 4 | - | - | - | .008 | .022 | .731 | .002 | .023 | .933 |
| |||||||||
AUC Cortisol | |||||||||
Intercept | 4.104 | .379 | <.001 | 3.672 | .389 | <.001 | 3.951 | .392 | <.001 |
Time since feeding (min)4 | .149 | .063 | .019 | .137 | .064 | .035 | .149 | .063 | .020 |
GA at birth (weeks)5 | −.094 | .045 | .036 | −.078 | .046 | .090 | −.102 | .045 | .026 |
Alcohol use7 | .470 | .347 | .178 | .351 | .353 | .321 | .494 | .349 | .158 |
Baseline cortisol (linear)4 | .644 | .083 | <.001 | .656 | .085 | <.001 | .637 | .084 | <.001 |
Baseline cortisol (quadratic)4 | .191 | .042 | <.001 | .205 | .044 | <.001 | .194 | .043 | <.001 |
Infant age (hours)4 | −.143 | .042 | <.001 | −.143 | .043 | <.001 | −.147 | .042 | <.001 |
MSDP | −.376 | .106 | <.001 | - | - | - | −.364 | .117 | .002 |
NR3C1 methylation CpG 3 | - | - | - | .085 | .048 | .079 | .049 | .049 | .318 |
NR3C1 methylation CpG 4 | - | - | - | .008 | .022 | .698 | −.010 | .022 | .655 |
Model with MSDP, but not NR3C1 methylation.
Model with NR3C1 methylation but not MSDP.
Model with NR3C1 methylation and MSDP.
Natural log transformed.
Centered at the mean.
0:≤200 mg/day, 1:>200 mg/day.
0:≤1 drink per week, 1:>1 drink per week.