Table 2. Egg consumption and atherosclerosis in NOMAS.
| N=1429 | cIMT (mean of the max) Beta, p-value | Plaque presence vs. no plaque OR (95% CI) | Plaque thickness 50% effect, p-value | Plaque thickness 75% effect, p-value | Plaque area 50% effect, p-value | Plaque area 75% effect, p-value |
|---|---|---|---|---|---|---|
| Egg consumption, continuous | ||||||
|
| ||||||
| Eggs/wk. | ||||||
| Model 1 | -0.00261, 0.09 | 0.92 (0.85-0.99) | -0.0652, 0.22 | -0.0401, 0.06 | -0.4449, 0.001 | -1.2347, 0.0001 |
| Model 2 | -0.00369, 0.01 | 0.90 (0.83-0.98) | -0.0958, <0.0001 | -0.0622, 0.01 | -0.2478, 0.01 | -1.1850, <0.0001 |
| Model 3 | -0.00328, 0.03 | 0.91 (0.83-0.99) | -0.0788, 0.001 | -0.0660, 0.01 | -0.1749, 0.18 | -1.0168, <0.0001 |
| Model 4 | -0.00379, 0.02 | 0.89 (0.82-0.97) | -0.0882, 0.001 | -0.0737, 0.003 | -0.3858, 0.001 | -1.1078, <0.0001 |
| Model 5 | -0.00296, 0.08 | 0.89 (0.81-0.98) | -0.0752, 0.003 | -0.0772, 0.003 | -0.2320, 0.09 | -1.0272, <0.0001 |
|
| ||||||
| Egg consumption, frequency | ||||||
|
| ||||||
| 0 or <1x/mo. | ref | ref | ref | ref | ref | ref |
|
| ||||||
| 1x/mo. | ||||||
| Model 1 | -0.00176, 0.78 | 0.99 (0.73-1.34) | 0.0000, 1.00 | -0.0712, 0.43 | -0.1633, 0.91 | 0.4337, 0.87 |
| Model 2 | -0.00353, 0.56 | 0.95 (0.69-1.30) | -0.1245, 0.43 | -0.0378, 0.71 | -1.4828, 0.11 | -0.5734, 0.78 |
| Model 3 | -0.00304, 0.62 | 0.96 (0.69-1.35) | -0.0443, 0.73 | 0.0593, 0.53 | -0.5599, 0.55 | -0.0322, 0.99 |
| Model 4 | -0.00304, 0.62 | 1.02 (0.73-1.43) | -0.0878, 0.54 | 0.0009, 0.99 | -0.5345, 0.57 | 0.4337, 0.83 |
| Model 5 | -0.00398, 0.52 | 0.93 (0.66-1.30) | -0.0400, 0.76 | -0.0131, 0.90 | -0.1380, 0.87 | -0.6972, 0.72 |
|
| ||||||
| 2-3 x/mo. | ||||||
| Model 1 | -0.01617, 0.02 | 0.67 (0.48-0.95) | -0.1739, 0.73 | -0.3321, 0.002 | -2.1734, 0.28 | -6.5917, 0.01 |
| Model 2 | -0.01752, 0.01 | 0.62 (0.43-0.89) | -0.5407, 0.01 | -0.2721, 0.02 | -2.7513, 0.001 | -8.5923, <0.0001 |
| Model 3 | -0.01724, 0.01 | 0.64 (0.44-0.93) | -0.3110, 0.06 | -0.1384, 0.29 | -1.9672, 0.04 | -6.2675, <0.0001 |
| Model 4 | -0.01717, 0.02 | 0.64 (0.44-0.94) | -0.3731, 0.02 | -0.1645, 0.17 | -2.2677, 0.02 | -5.7141, 0.0002 |
| Model 5 | -0.01691, 0.02 | 0.63 (0.43-0.92) | -0.3935, 0.01 | -0.1437, 0.23 | -1.8842, 0.03 | -5.3846, 0.0003 |
|
| ||||||
| 1x/wk. | ||||||
| Model 1 | -0.01460, 0.01 | 0.78 (0.58-1.04) | -0.0870, 0.53 | -0.2451, 0.003 | -0.6224, 0.63 | -3.8163, 0.08 |
| Model 2 | -0.0181, 0.002 | 0.73 (0.54-0.99) | -0.3723, 0.04 | -0.2108, 0.03 | -2.4067, 0.0003 | -5.2935, 0.001 |
| Model 3 | -0.0176, 0.003 | 0.72 (0.52-1.00) | -0.2818, 0.02 | -0.1061, 0.28 | -1.2815, 0.11 | -4.0597, 0.004 |
| Model 4 | -0.0196, 0.002 | 0.68 (0.49-0.95) | -0.3790, 0.003 | -0.1340, 0.21 | -1.6238, 0.03 | -3.9503, 0.01 |
| Model 5 | -0.0184, 0.004 | 0.66 (0.47-0.94) | -0.2674, 0.03 | -0.1886, 0.06 | -1.6685, 0.02 | -3.5808, 0.03 |
|
| ||||||
| ≥2x/wk. | ||||||
| Model 1 | -0.00833, 0.44 | 0.70 (0.42-1.18) | -0.0852, 0.90 | -0.1892, 0.16 | -3.3163, 0.19 | -3.2397, 0.41 |
| Model 2 | -0.01632, 0.12 | 0.63 (0.36-1.09) | -0.5729, 0.004 | -0.1437, 0.33 | -2.0621, 0.13 | -7.3400, 0.001 |
| Model 3 | -0.01414, 0.19 | 0.64 (0.36-1.15) | -0.3945, 0.04 | -0.2095, 0.34 | -1.4839, 0.24 | -5.0906, 0.08 |
| Model 4 | -0.01768, 0.11 | 0.59 (0.32-1.10) | -0.5132, 0.01 | -0.3030, 0.18 | -2.1244,0.09 | -5.7478, 0.05 |
| Model 5 | -0.01324, 0.25 | 0.58 (0.31-1.07) | -0.3745, 0.09 | -0.3472, 0.13 | -1.6186, 0.16 | -4.9831, 0.12 |
cIMT, carotid intima media thickness; CI, confidence interval; wk., week; mo., month
Model 1: unadjusted; Model 2: adjusted for age, sex, race/ethnicity; Model 3: adjusted for variables in model 1 + BMI, diabetes, hypertension, LDL, HDL, TG, cholesterol-lowering medication, moderate alcohol use, moderate-heavy physical activity, smoking, high-school completion; Model 4: adjusted for variables in model 3 + total daily kilocalories, MEDI diet score; Model 5: adjusted for variables in model 3 + family history of stroke in siblings, family history of MI in siblings, daily consumption of saturated fat, unsaturated fat, carbohydrates, and protein