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. 1979 Feb;23(2):540–544. doi: 10.1128/iai.23.2.540-544.1979

Murine neurotropic retrovirus spongiform polioencephalomyelopathy: acceleration of disease by virus inoculum concentration.

B R Brooks, J R Swarz, O Narayan, R T Johnson
PMCID: PMC414197  PMID: 217835

Abstract

A 10-fold reduction in the incubation period of murine neurotropic retrovirus spongiform polioencephalomyelopathy was effected by a 1,000-fold concentration of the cloned virus inoculum.

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Selected References

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  1. Bronson D. L., Elliott A. Y., Ritzi D. A comparison of four methods used to concentrate Rous sarcoma virus from tissue culture fluids. J Gen Virol. 1976 Dec;33(3):403–410. doi: 10.1099/0022-1317-33-3-403. [DOI] [PubMed] [Google Scholar]
  2. Croker B. P., Jr, del Villano B. C., Jensen F. C., Lerner R. A., Dixon F. J. Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus. J Exp Med. 1974 Oct 1;140(4):1028–1048. doi: 10.1084/jem.140.4.1028. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Duesberg P. H., Robinson W. S. Nucleic acid and proteins isolated from the Rauscher mouse leukemia virus (MLV). Proc Natl Acad Sci U S A. 1966 Jan;55(1):219–227. doi: 10.1073/pnas.55.1.219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gajdusek D. C. Unconventional viruses and the origin and disappearance of kuru. Science. 1977 Sep 2;197(4307):943–960. doi: 10.1126/science.142303. [DOI] [PubMed] [Google Scholar]
  5. Gardner M. B. Type C viruses of wild mice: characterization and natural history of amphotropic, ecotropic, and xenotropic MuLv. Curr Top Microbiol Immunol. 1978;79:215–259. doi: 10.1007/978-3-642-66853-1_5. [DOI] [PubMed] [Google Scholar]
  6. Haase A. T., Baringer J. R. The structural polypeptides of RNA slow viruses. Virology. 1974 Jan;57(1):238–250. doi: 10.1016/0042-6822(74)90124-x. [DOI] [PubMed] [Google Scholar]
  7. Hartley J. W., Rowe W. P. Clonal cells lines from a feral mouse embryo which lack host-range restrictions for murine leukemia viruses. Virology. 1975 May;65(1):128–134. doi: 10.1016/0042-6822(75)90013-6. [DOI] [PubMed] [Google Scholar]
  8. Hartley J. W., Rowe W. P. Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class. J Virol. 1976 Jul;19(1):19–25. doi: 10.1128/jvi.19.1.19-25.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Hartley J. W., Wolford N. K., Old L. J., Rowe W. P. A new class of murine leukemia virus associated with development of spontaneous lymphomas. Proc Natl Acad Sci U S A. 1977 Feb;74(2):789–792. doi: 10.1073/pnas.74.2.789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kimberlin R. H., Walker C. Characteristics of a short incubation model of scrapie in the golden hamster. J Gen Virol. 1977 Feb;34(2):295–304. doi: 10.1099/0022-1317-34-2-295. [DOI] [PubMed] [Google Scholar]
  11. Mathes L. E., Yohn D. S., Olsen R. G. Purification of infectious feline leukemia virus from large volumes of tissue culture fluids. J Clin Microbiol. 1977 Mar;5(3):372–374. doi: 10.1128/jcm.5.3.372-374.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Narayan O., Griffin D. E., Silverstein A. M. Slow virus infection: replication and mechanisms of persistence of visna virus in sheep. J Infect Dis. 1977 May;135(5):800–806. doi: 10.1093/infdis/135.5.800. [DOI] [PubMed] [Google Scholar]
  13. Oldstone M. B., Lampert P. W., Lee S., Dixon F. J. Pathogenesis of the slow disease of the central nervous system associated with WM 1504 E virus. I. Relationship of strain susceptibility and replication to disease. Am J Pathol. 1977 Jul;88(1):193–212. [PMC free article] [PubMed] [Google Scholar]
  14. Rowe W. P., Pugh W. E., Hartley J. W. Plaque assay techniques for murine leukemia viruses. Virology. 1970 Dec;42(4):1136–1139. doi: 10.1016/0042-6822(70)90362-4. [DOI] [PubMed] [Google Scholar]
  15. Wear D. J., Rabin E. R., Richardson L. S., Rapp F. Virus replication and ultrastructural changes after induction of encephalitis in mice by measles virus. Exp Mol Pathol. 1968 Dec;9(3):405–417. doi: 10.1016/0014-4800(68)90029-4. [DOI] [PubMed] [Google Scholar]

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