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. 1979 Sep;25(3):1078–1080. doi: 10.1128/iai.25.3.1078-1080.1979

Effect of visceral leishmaniasis on congenitally athymic mice.

L L Smrkovski, C L Larson, S G Reed
PMCID: PMC414558  PMID: 159259

Abstract

Congenitally athymic mice were more susceptible to challenge with amastigotes of Leishmania donovani than were their thymus-intact littermates. This increased susceptibility correlated with a lack of Arthus and delayed-type responses when animals were skin tested with leishmanial antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bryceson A. D., Bray R. S., Dumonde D. C. Experimental cutaneous leishmaniasis. IV. Selective suppression of cell-mediated immunity during the response of guinea-pigs to infection with Leishmania enriettii. Clin Exp Immunol. 1974 Feb;16(2):189–202. [PMC free article] [PubMed] [Google Scholar]
  2. Bryceson A. D., Preston P. M., Bray R. S., Dumonde D. C. Experimental cutaneous leishmaniasis. II. Effects of immunosuppression and antigenic competition on the course of infection with Leishmania enriettii in the guinea-pig. Clin Exp Immunol. 1972 Feb;10(2):305–335. [PMC free article] [PubMed] [Google Scholar]
  3. CONVIT J., REYES O., KERDEL F. Disseminated anergic American leishmaniasis; report of three cases of a type clinically resembling lepromatous leprosy. AMA Arch Derm. 1957 Aug;76(2):213–217. doi: 10.1001/archderm.1957.01550200057012. [DOI] [PubMed] [Google Scholar]
  4. Campbell G. H., Esser K. M., Phillips S. M. Trypanosoma rhodesiense infection in congenitally athymic (nude) mice. Infect Immun. 1978 Jun;20(3):714–720. doi: 10.1128/iai.20.3.714-720.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Convit J., Pinardi M. E., Rondón A. J. Diffuse cutaneous leishmaniasis: a disease due to an immunological defect of the host. Trans R Soc Trop Med Hyg. 1972;66(4):603–610. doi: 10.1016/0035-9203(72)90306-9. [DOI] [PubMed] [Google Scholar]
  6. ELBERG S. S., SCHNEIDER P., FONG J. Cross-immunity between Brucella melitensis and Mycobacterium tuberculosis; intracellular behavior of Brucella melitensis in monocytes from vaccinated animals. J Exp Med. 1957 Oct 1;106(4):545–554. doi: 10.1084/jem.106.4.545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Garnham P. C., Humphrey J. H. Problems in leishmaniasis related to immunology. Curr Top Microbiol Immunol. 1969;48:29–42. doi: 10.1007/978-3-642-46163-7_2. [DOI] [PubMed] [Google Scholar]
  8. LARSON C. L., WICHT W. C. Studies of resistance to experimental tuberculosis in mice vaccinated with living attenuated tubercle bacilli and challenged with virulent organisms. Am Rev Respir Dis. 1962 Jun;85:833–846. doi: 10.1164/arrd.1962.85.6.833. [DOI] [PubMed] [Google Scholar]
  9. Munro D. D., Du Vivier A., Jopling W. H. Post kala-azar dermal leishmaniasis. Br J Dermatol. 1972 Oct;87(4):374–378. doi: 10.1111/j.1365-2133.1972.tb07425.x. [DOI] [PubMed] [Google Scholar]
  10. Osebold J. W., Pearson L. D., Medin N. I. Relationship of antimicrobial cellular immunity to delayed hypersensitivity in Listeriosis. Infect Immun. 1974 Feb;9(2):354–362. doi: 10.1128/iai.9.2.354-362.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Preston P. M., Carter R. L., Leuchars E., Davies A. J., Dumonde D. C. Experimental cutaneous leishmaniasis. 3. Effects of thymectomy on the course of infection of CBA mice with Leishmania tropica. Clin Exp Immunol. 1972 Feb;10(2):337–357. [PMC free article] [PubMed] [Google Scholar]
  12. Preston P. M., Tsega E., Dumonde D. C. Enhanced susceptibility of thymectomized mice to infection with Leishmania tropica. Trans R Soc Trop Med Hyg. 1971;65(1):18–18. [PubMed] [Google Scholar]
  13. Smrkovski L. L., Larson C. L. Antigenic cross-reactivity between Mycobacterium bovis (BCG) and Leishmania donovani. Infect Immun. 1977 Nov;18(2):561–562. doi: 10.1128/iai.18.2.561-562.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Smrkovski L. L., Larson C. L. Effect of treatment with BCG on the course of visceral leishmaniasis in BALB/c mice. Infect Immun. 1977 Apr;16(1):249–257. doi: 10.1128/iai.16.1.249-257.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Smrkovski L. L., Larson C. L., Sogandares-Bernal F. Fatal visceral leishmaniasis in a strain of Swiss mice. J Parasitol. 1974 Aug;60(4):718–719. [PubMed] [Google Scholar]

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