There is an error in affiliation 4 for Hafid Laayouni. Affiliation 4 should be:
Department de Genètica i de Microbiologia, Grup de Biologia Evolutiva (GBE), Universitat Autonòma de Barcelona, Bellaterra (Barcelona), Spain
Additionally, Table 1 is formatted incorrectly. Please refer to the correct Table 1 here:
Table 1. Regions showing top scores in the genome.
region | criteria | Closest gene | Distance to closest gene | Description of closest gene | 2nd closest gene | Description of 2nd closest gene |
chr2:91959344-91968231 | high number of components | GGT8P | inside gene | pseudogene | ||
chr6:33037767-33038449 | high number of components | HLA-DPA1 / HLA-DPB1 | inside gene | Homo sapiens major histocompatibility complex, class II | ||
chr:7203189-7420319641 | high number of components | ITGB8 | 50,684 bp | integrin | HLA-DPA1 / HLA-DPB1 | major histocompatibility complex, class II |
chr5:108634323-108635534 | high average degree | PJA2 | 34,876 bp | praja ring finger 2, E3 ubiquitin protein ligase | AK021888 | unknown function |
chr8:25935936-25937929 | high average degree | EBF2 | inside gene | early B-cell factor 2 | ||
chr6:32507854-32508257 | high average path length | HLA-DRB1 | inside gene | Homo sapiens major histocompatibility complex, class II | ||
chr6:32568909-32569343 | high average path length | HLA-DRB5 | 11,297 bp | Homo sapiens major histocompatibility complex, class II | HLA-DQA1 | major histocompatibility complex, class II |
chr6:32611264-32611586 | high average path length | HLA-DQA1 | inside gene | Homo sapiens major histocompatibility complex, class II | ||
chr3:36921415-36921688 | high number of vertices | TRANK1 | inside gene | tetratricopeptide repeat and ankyrin repeat Containing 1 | ||
chr4:9176678-9178624 | high number of vertices | C9JJH3 | 33,759 bp | Deubiquitinating enzyme | LOC650293 | transmembrane helix receptor |
chr8:35105546-35106981 | high number of vertices | UNC5D | inside gene | receptor of netrin involved in nervous system | ||
chr4:9200148-9202368 | few components, but large number of vertices | USP17L10 | 10,015 bp | Deubiquitinating enzyme | ||
chr6:31357915-31358747 | few components, but large number of vertices | MICA | 8,814 bp | MHC class I polypeptide-related sequence A | HLA-B | major histocompatibility complex, class I |
chr6:31455010-31456012 | few components, but large number of vertices | MICB | 6,646 bp | MHC class I polypeptide-related Sequence B | uc003ntm.3 | HLA complex Group 26 (non-protein coding) |
Reference
- 1. Dall'Olio GM, Bertranpetit J, Wagner A, Laayouni H (2014) Human Genome Variation and the Concept of Genotype Networks. PLoS ONE 9(6): e99424 doi:10.1371/journal.pone.0099424 [DOI] [PMC free article] [PubMed] [Google Scholar]