Skip to main content
NCBI home page
Infection and Immunity logoLink to Infection and Immunity
. 1979 Dec;26(3):1214–1217. doi: 10.1128/iai.26.3.1214-1217.1979

Inhibition of adsorption of Streptococcus mutans strains to saliva-treated hydroxyapatite by galactose and certain amines.

R J Gibbons, J V Qureshi
PMCID: PMC414749  PMID: 528053

Abstract

Adsorption of all of eight strains of Streptococcus mutans to saliva-treated hydroxyapatite (S-HA) surfaces was inhibited by galactose and melibiose, but not by other neutral sugars tested. This observation supports the hypothesis that lectin-like components participate in the attachment of these streptococci to salivary glycoproteins on saliva-treated hydroxyapatite surfaces. Adsorption of all strains was also inhibited by iodoacetate and spermine; other amines tested reduced adsorption of some strains, but not others.

Full text

PDF
1214

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Clark W. B., Bammann L. L., Gibbons R. J. Ability of Streptococcus mutans and a glucosyltransferase-defective mutant to colonize rodents and attach to hydroxyapatite surfaces. Infect Immun. 1978 Aug;21(2):681–684. doi: 10.1128/iai.21.2.681-684.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Clark W. B., Bammann L. L., Gibbons R. J. Comparative estimates of bacterial affinities and adsorption sites on hydroxyapatite surfaces. Infect Immun. 1978 Mar;19(3):846–853. doi: 10.1128/iai.19.3.846-853.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Clark W. B., Gibbons R. J. Influence of salivary components and extracellular polysaccharide synthesis from sucrose on the attachment of Streptococcus mutans 6715 to hydroxyapatite surfaces. Infect Immun. 1977 Nov;18(2):514–523. doi: 10.1128/iai.18.2.514-523.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Ericson T. Salivary glycoproteins. Composition and adsorption to hydroxylapatite in relation to the formation of dental pellicles and calculus. Acta Odontol Scand. 1968 May;26(1):3–21. doi: 10.3109/00016356809004577. [DOI] [PubMed] [Google Scholar]
  5. Gibbons R. J., Fitzgerald R. J. Dextran-induced agglutination of Streptococcus mutans, and its potential role in the formation of microbial dental plaques. J Bacteriol. 1969 May;98(2):341–346. doi: 10.1128/jb.98.2.341-346.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Gibbons R. J., Qureshi J. V. Selective binding of blood group-reactive salivary mucins by Streptococcus mutans and other oral organisms. Infect Immun. 1978 Dec;22(3):665–671. doi: 10.1128/iai.22.3.665-671.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gibbons R. J., van Houte J. Dental caries. Annu Rev Med. 1975;26:121–136. doi: 10.1146/annurev.me.26.020175.001005. [DOI] [PubMed] [Google Scholar]
  8. Hamada S., Gill K., Slade H. D. Binding of lectins to Streptococcus mutans cells and type-specific polysaccharides, and effect on adherence. Infect Immun. 1977 Dec;18(3):708–716. doi: 10.1128/iai.18.3.708-716.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Levine M. J., Herzberg M. C., Levine M. S., Ellison S. A., Stinson M. W., Li H. C., van Dyke T. Specificity of salivary-bacterial interactions: role of terminal sialic acid residues in the interaction of salivary glycoproteins with Streptococcus sanguis and Streptococcus mutans. Infect Immun. 1978 Jan;19(1):107–115. doi: 10.1128/iai.19.1.107-115.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Russell R. R. Glucan-binding proteins of Streptococcus mutans serotype c. J Gen Microbiol. 1979 May;112(1):197–201. doi: 10.1099/00221287-112-1-197. [DOI] [PubMed] [Google Scholar]
  11. Rölla G. Formation of dental integuments--some basic chemical considerations. Swed Dent J. 1977;1(6):241–251. [PubMed] [Google Scholar]
  12. Rölla G., Robrish S. A., Bowen W. H. Interaction of hydroxyapatite and protein-coated hydroxyapatite with Streptococcus mutans and Streptococcus sanguis. Acta Pathol Microbiol Scand B. 1977 Oct;85B(5):341–346. doi: 10.1111/j.1699-0463.1977.tb01985.x. [DOI] [PubMed] [Google Scholar]
  13. Spinell D. M., Gibbons R. J. Influence of culture medium on the glucosyl transferase- and dextran-binding capacity of Streptococcus mutans 6715 cells. Infect Immun. 1974 Dec;10(6):1448–1451. doi: 10.1128/iai.10.6.1448-1451.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Staat R. H., Doyle R. J., Langley S. D., Suddick R. P. Modification of in vitro adherence of Streptococcus mutans by plant lectins. Adv Exp Med Biol. 1978;107:639–647. doi: 10.1007/978-1-4684-3369-2_72. [DOI] [PubMed] [Google Scholar]
  15. Sönju T., Christensen T. B., Kornstad L., Rölla G. Electron microscopy, carbohydrate analyses and biological activities of the proteins adsorbed in two hours to tooth surfaces in vivo. Caries Res. 1974;8(2):113–122. doi: 10.1159/000260099. [DOI] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES