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. 1974 Jan;9(1):41–43. doi: 10.1128/iai.9.1.41-43.1974

Passive Transfer of Delayed-Type Hypersensitivity to Cell Walls of Staphylococcus aureus

S P Targowski a,1, David T Berman a
PMCID: PMC414761  PMID: 4808852

Abstract

Protracted inflammatory dermal reactions to staphylococcal cell walls were observed in guinea pigs passively sensitized by transfer of peritoneal exudate cells but not by immune serum from guinea pigs actively sensitized with heat-killed cells of Staphylococcus aureus. The experiments verify the hypothesis that the protracted reaction is a cell-mediated immune response which is resolvable from the toxicity of the cell walls.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Heymer B., Bültmann B., Haferkamp O. Toxicity of streptococcal mucopeptides in vivo and in vitro. J Immunol. 1971 Mar;106(3):858–861. [PubMed] [Google Scholar]
  2. JOHANOVSKY J. Role of hypersensitivity in experimental staphylococcal infection. Nature. 1958 Nov 22;182(4647):1454–1454. doi: 10.1038/1821454a0. [DOI] [PubMed] [Google Scholar]
  3. Kowalski J. J., Berman D. T. Immunobiological activity of cell wall antigens of Staphylococcus aureus. Infect Immun. 1971 Sep;4(3):205–211. doi: 10.1128/iai.4.3.205-211.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kowalski J. J., Tipper D. J., Berman D. T. Preparation of Cell Wall Antigens of Staphylococcus aureus. Infect Immun. 1970 Jul;2(1):54–59. doi: 10.1128/iai.2.1.54-59.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Mudd S., Taubler J. H., Baker A. G. Delayed-type hypersensitivity to Staphylococcus aureus in human subjects. J Reticuloendothel Soc. 1970 Nov;8(5):493–498. [PubMed] [Google Scholar]
  6. Schuster G. S., Hayashi J. A., Bahn A. N. Toxic properties of the cell wall of gram-positive bacteria. J Bacteriol. 1967 Jan;93(1):47–52. doi: 10.1128/jb.93.1.47-52.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Taubler J. H., Grieb M., Mudd S. Immunologically Induced and Elicited Local Resistance to Staphylococcus aureus. Infect Immun. 1970 Dec;2(6):757–761. doi: 10.1128/iai.2.6.757-761.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Taubler J. H., Mudd S. Staphylococcal delayed hypersensitivity in mice. II. In vitro demonstration and specificity of delayed hypersensitivity. J Immunol. 1968 Sep;101(3):550–555. [PubMed] [Google Scholar]
  9. Taubler J. H. Staphylococcal delayed hypersensitivity in mice. I. Induction and in vivo demonstration of delayed hypersensitivity. J Immunol. 1968 Sep;101(3):546–549. [PubMed] [Google Scholar]

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