Table 1. Analysis of the correlations between nuclear, cytoplasmic, and overall MTA1 with the clinicopathological parameters of colon cancer.
Total | Nuclear Intensity | Mean rank | P value | Cytoplasmic Intensity | Mean rank | P value | Overall Intensity | Mean rank | P value | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | ||||||||
Age, years | |||||||||||||||||||
≤60 | 153 | 10 | 58 | 71 | 14 | 136.83 | 0.537 | 8 | 73 | 50 | 22 | 138.37 | 0.302 | 9 | 63 | 60 | 21 | 139.62 | 0.178 |
>60 | 115 | 10 | 43 | 55 | 7 | 131.40 | 5 | 60 | 44 | 6 | 129.36 | 8 | 53 | 46 | 8 | 127.69 | |||
Differen tiation |
|||||||||||||||||||
Well | 28 | 8 | 16 | 4 | 0 | 69.93 | 0.000 | 3 | 15 | 5 | 5 | 123.61 | 0.527 | 3 | 12 | 7 | 6 | 134.38 | 0.506 |
Moderate | 190 | 11 | 68 | 99 | 12 | 138.45 | 7 | 93 | 70 | 20 | 137.49 | 12 | 76 | 84 | 18 | 137.28 | |||
Poor | 50 | 1 | 17 | 23 | 9 | 155.66 | 3 | 25 | 19 | 3 | 129.22 | 2 | 28 | 15 | 5 | 123.99 | |||
Clinical stage | |||||||||||||||||||
I | 22 | 9 | 13 | 0 | 0 | 46.25 | 0.000 | 5 | 15 | 2 | 0 | 73.73 | 0.000 | 10 | 10 | 2 | 0 | 55.36 | 0.000 |
II | 218 | 11 | 77 | 111 | 19 | 142.04 | 8 | 101 | 81 | 28 | 141.91 | 7 | 85 | 97 | 29 | 146.50 | |||
III | 21 | 0 | 6 | 13 | 2 | 159.07 | 0 | 13 | 8 | 0 | 123.24 | 0 | 16 | 5 | 0 | 101.93 | |||
IV | 7 | 0 | 5 | 2 | 0 | 103.43 | 0 | 4 | 3 | 0 | 128.64 | 0 | 5 | 2 | 0 | 107.21 | |||
Tumor status | |||||||||||||||||||
T1 | 4 | 1 | 3 | 0 | 0 | 55.88 | 0.000 | 1 | 3 | 0 | 0 | 61.75 | 0.003 | 2 | 2 | 0 | 0 | 42.25 | 0.000 |
T2 | 20 | 8 | 10 | 2 | 0 | 58.15 | 4 | 12 | 4 | 0 | 88.10 | 8 | 8 | 4 | 0 | 71.10 | |||
T3 | 156 | 8 | 60 | 74 | 14 | 138.52 | 8 | 71 | 54 | 23 | 141.27 | 6 | 60 | 68 | 22 | 146.50 | |||
T4 | 88 | 3 | 28 | 50 | 7 | 148.30 | 0 | 47 | 36 | 5 | 136.35 | 1 | 46 | 34 | 7 | 131.83 | |||
Metastasis | |||||||||||||||||||
N0M0 | 191 | 18 | 80 | 82 | 11 | 124.80 | 0.000 | 12 | 102 | 68 | 9 | 124.04 | 0.000 | 16 | 83 | 81 | 11 | 127.28 | 0.009 |
N1-N2,NOM1 | 77 | 2 | 21 | 44 | 10 | 158.57 | 1 | 31 | 26 | 19 | 160.44 | 1 | 33 | 25 | 18 | 152.40 | |||
Total | 268 | 20 | 101 | 126 | 21 | 13 | 133 | 94 | 28 | 17 | 116 | 106 | 29 | ||||||
Mann-Whitney U test for age and metastasis analysis | |||||||||||||||||||
Kruskal-Wallis H (K) test for differentiation, clinical stage and tumor status analysis |