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. 1974 Apr;9(4):648–653. doi: 10.1128/iai.9.4.648-653.1974

In Vitro Production of N-Nitrosodimethylamine and Other Amines by Proteus Species

L Thacker 1, J B Brooks 1
PMCID: PMC414859  PMID: 4595755

Abstract

N-nitrosodimethylamine, a potent carcinogen, was produced by three strains each of Proteus mirabilis, P. morganii, and P. rettgeri, but not by three strains of P. vulgaris grown under the same conditions. Many of the alkaline-extractable volatile metabolites elaborated by these organisms are the same, but there are some qualitative and quantitative differences among species. Representative gas-liquid chromatographic profiles of the four species are presented, and the significance of the differences is discussed. Primary emphasis, however, is given to the importance of the production of N-nitrosodimethylamine by these microorganisms and the conditions under which it is produced.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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