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. 1974 Aug;10(2):369–374. doi: 10.1128/iai.10.2.369-374.1974

Persistence of Diplococcus pneumoniae after Influenza Virus Infection in Macaca mulatta

Richard F Berendt 1, William E McDonough 1, Jerry S Walker 1
PMCID: PMC415007  PMID: 4152991

Abstract

Exposure of monkeys to aerosols of influenza virus followed later by aerosols of Diplococcus pneumoniae resulted in persistence of the bacteria in the upper respiratory tract for an average of 28 days. Examination of selected tissues for pneumococci revealed that pneumococci were widely disseminated throughout the respiratory tract at 3 and 7 days after exposure, but were cleared from lower respiratory tissues and were found mainly in tonsils, oropharynx, and posterior nasopharynx after 14 days.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ammann A. J., Pelger R. J. Determination of antibody to pneumococcal polysaccharides with chromic chloride-treated human red blood cells and indirect hemagglutination. Appl Microbiol. 1972 Nov;24(5):679–683. doi: 10.1128/am.24.5.679-683.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Berendt R. F. Simian model for the evaluation of immunity to influenza. Infect Immun. 1974 Jan;9(1):101–105. doi: 10.1128/iai.9.1.101-105.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. GERONE P. J., WARD T. G., CHAPPELL W. A. Combined infections in mice with influenza virus and Diplococcus pneumoniae. Am J Hyg. 1957 Nov;66(3):331–341. doi: 10.1093/oxfordjournals.aje.a119906. [DOI] [PubMed] [Google Scholar]
  4. HERS J. F., MASUREL N., MULDER J. Bacteriology and histopathology of the respiratory tract and lungs in fatal Asian influenza. Lancet. 1958 Nov 29;2(7057):1141–1143. doi: 10.1016/s0140-6736(58)92404-8. [DOI] [PubMed] [Google Scholar]
  5. Johanson W. G., Pierce A. K., Sanford J. P. Changing pharyngeal bacterial flora of hospitalized patients. Emergence of gram-negative bacilli. N Engl J Med. 1969 Nov 20;281(21):1137–1140. doi: 10.1056/NEJM196911202812101. [DOI] [PubMed] [Google Scholar]
  6. Loosli C. G. Influenza and the interaction of viruses and bacteria in respiratory infections. Medicine (Baltimore) 1973 Sep;52(5):369–384. doi: 10.1097/00005792-197309000-00001. [DOI] [PubMed] [Google Scholar]
  7. MALLIGO J. E., IDOINE L. S. SINGLE-STAGE IMPACTION DEVICE FOR PARTICLE SIZING BIOLOGICAL AEROSOLS. Appl Microbiol. 1964 Jan;12:32–36. doi: 10.1128/am.12.1.32-36.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Meiklejohn G. Control of smallpox and influenza. J Infect Dis. 1973 Feb;127(2):215–219. doi: 10.1093/infdis/127.2.215. [DOI] [PubMed] [Google Scholar]
  9. PETERSDORF R. G., FUSCO J. J., HARTER D. H., ALBRINK W. S. Pulmonary infections complicating Asian influenza. AMA Arch Intern Med. 1959 Feb;103(2):262–272. doi: 10.1001/archinte.1959.00270020090010. [DOI] [PubMed] [Google Scholar]
  10. ROBERTSON L., CALEY J. P., MOORE J. Importance of Staphylococcus aureus in pneumonia in the 1957 epidemic of influenza A. Lancet. 1958 Aug 2;2(7040):233–236. doi: 10.1016/s0140-6736(58)90060-6. [DOI] [PubMed] [Google Scholar]
  11. Sawyer W. D. Interaction of influenza virus with leukocytes and its effect on phagocytosis. J Infect Dis. 1969 Jun;119(6):541–556. doi: 10.1093/infdis/119.6.541. [DOI] [PubMed] [Google Scholar]

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