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. 1975 Jan;11(1):137–141. doi: 10.1128/iai.11.1.137-141.1975

Immune response to hepatitis B surface antigen.

A B Ibrahim, G N Vyas, H A Perkins
PMCID: PMC415036  PMID: 1116872

Abstract

A total of 69 persons were investigated for assessment of cell-mediated and humoral immunity to hepatitis B surface antigen (HBsAg). Three groups, each consisting of 20 normal persons, 20HBsAg carriers, and 20 convalescent hepatitis B patients, were studied for HBsAg, anti-HBs, and leukocyte migration inhibition with purified HBsAg. Sequential sampling if an additional group of nine acute hepatitis B patients defined the cellular and humoral immune response to HBsAg. The antigen was eliminated rapidly by mounting of cell-mediated immune response detectable for a limited period, followed by antibody response in relatively few patients moore than 3 months after clearance of circulating HBsAg.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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