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. 1975 Jan;11(1):142–145. doi: 10.1128/iai.11.1.142-145.1975

Hepatitis B antigen in saliva, urine, and stool.

G R Irwin, A M Allen, W H Bancroft, J J Karwacki, H L Brown, R H Pinkerton, M Willhight, F H Top Jr
PMCID: PMC415037  PMID: 1116873

Abstract

A survey of hepatitis B patients, asymptomatic hepatitis B antigen (HBsAg) carriers, and control subjects was conducted to determine the relationship between antigenemia and antigen excretion in saliva, urine, and stool. Radioimmunoassay was used to detect HBsAg. Specificity-confirmed HBsAg was detected in the saliva of 6 (30%) of 20 antigenemic patients, 1 (5%) of 20 nonantigenemic patients, 14 (34%) of 41 carriers, and 0 of 112 controls. HBsAg was detected in urine only after 100-fold concentration of first-morning specimens. Specificity-confirmed HBsAg was present in the urine of 7 (16%) of 43 carriers; unconfirmed HBsAg was found in the urine of 5 (13%) of 38 patients and 5 (5%) of 112 controls. Unconfirmed HBsAg was detected in concentrated stool specimens from 5 (46%) of 11 patients and 3 of 8 carriers and controls. Longitudinally collected specimens from antigenemic subjects showed no consistent patterns of antigen excretion.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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