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. 1975 Mar;11(3):551–555. doi: 10.1128/iai.11.3.551-555.1975

Newly recognized distinctive M protein associated with certain M type 1 group A streptococci.

A E Kholy, N I Guirguis, L W Wannamaker, R M Krause
PMCID: PMC415100  PMID: 803929

Abstract

Immunological and epidemiological characteristics of M1T1 and M1T8 (T8, 25, Imp.19) group A streptococci isolated in Egypt have been described. Both strains possess a common M1 antigen. The M1T8 strains possess a second antigen which has the immunological and biological characteristics of M protein. The M1T1 strains do not possess this second M antigen. Absorbed rabbit antisera which are specific for this second antigen do not react with extracts of any of the known M protein serotypes. This second antigen is therefore a newly recognized M protein. The M1T1 and M1T8 strains had mutually exclusive geographical and temporal distributions. This finding may have been a consequence of the immunity which occurred after the initial occurrence of the M1T8 strain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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