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. Author manuscript; available in PMC: 2014 Sep 2.
Published in final edited form as: Small. 2011 May 24;7(15):2232–2240. doi: 10.1002/smll.201002317

Figure 4.

Figure 4

TEM images of SERS nanoparticle accumulation in liver tissue at 5 min and 2 weeks post injection of SERS nanoparticles. a) Bright-field scanning TEM (STEM) image of liver tissue from mouse injected IR at 5 min. b) Bright-field STEM image of liver tissue from mouse injected IV at 5 min. Inset is a magnified view of the SERS nanoparticles boxed in the STEM image (scale bar = 250 nm). c) Bright-field STEM image of liver tissue from mouse injected IR at 2 weeks. d) Bright-field STEM image of liver tissue from mouse injected IV at 2 weeks. Inset is a magnified view of the SERS nanoparticles boxed in the STEM image (scale bar = 250 nm). Notice the absence of SERS nanoparticles in the liver tissue from the mice that received an IR injection, as shown in panels (a) and (c).