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. 1975 May;11(5):1010–1013. doi: 10.1128/iai.11.5.1010-1013.1975

Significane of intravascular coagulation in canine endotoxin shock.

A H From, W W Spink, D Knight, H Gewurz
PMCID: PMC415173  PMID: 1091556

Abstract

The contribution of disseminated fibrin clot formation to the pathogenesis of canine endotoxin shock was explored in control dogs and in those defibrinated with a purified fraction of Malayan pit viper venom. The hemodynamic and humoral responses after the administration of an intravenous challenge dose of Escherichia coli endotoxin were comparable as was mortality. It is concluded that, although the role of the coagulation sequence in canine endotoxin shock is unclear, it does not appear to be determinative.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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