Skip to main content
NCBI home page
Infection and Immunity logoLink to Infection and Immunity
. 1975 Jul;12(1):36–41. doi: 10.1128/iai.12.1.36-41.1975

Activation of mouse peritoneal cells to kill Listeria monocytogenes by T-lymphocyte products.

P Cole
PMCID: PMC415241  PMID: 806534

Abstract

An in vitro system has been used to demonstrate that glass-adherent mouse peritoneal cells can be activated to kill intracellular Listeria monocytogenes by antigen-stimulated T-lymphocytes derived from immunized mice. The soluble products of such stimulated lymphocyte cultures could only be shown to similarly activate peritoneal cells if the antigen used in both the immunization and lymphocyte stimulation was also present on the target intracellular organism.

Full text

PDF
36

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adler W. H., Takiguchi T., Marsh B., Smith R. T. Cellular recognition by mouse lymphocytes in vitro. I. Definition of a new technique and results of stimulation by phytohemagglutinin and specific antigens. J Exp Med. 1970 Jun 1;131(6):1049–1078. doi: 10.1084/jem.131.6.1049. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Blanden R. V., Langman R. E. Cell-mediated immunity to bacterial infection in the mouse. Thymus-derived cells as effectors of acquired resistance to Listeria monocytogenes. Scand J Immunol. 1972;1(4):379–391. doi: 10.1111/j.1365-3083.1972.tb03304.x. [DOI] [PubMed] [Google Scholar]
  3. Jones T., Youmans G. P. The in vitro inhibition of growth of intracellular Listeria monocytogenes by lymphocyte products. Cell Immunol. 1973 Dec;9(3):353–362. doi: 10.1016/0008-8749(73)90050-6. [DOI] [PubMed] [Google Scholar]
  4. Krahenbuhl J. L., Remington J. S. In vitro induction of nonspecific resistance in macrophages by specifically sensitized lymphocytes. Infect Immun. 1971 Oct;4(4):337–343. doi: 10.1128/iai.4.4.337-343.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Krahenbuhl J. L., Rosenberg L. T., Remington J. S. The role of thymus-derived lymphocytes in the in vitro activation of macrophages to kill Listeria monocytogenes. J Immunol. 1973 Oct;111(4):992–995. [PubMed] [Google Scholar]
  6. MACKANESS G. B. Cellular resistance to infection. J Exp Med. 1962 Sep 1;116:381–406. doi: 10.1084/jem.116.3.381. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Mackaness G. B. The influence of immunologically committed lymphoid cells on macrophage activity in vivo. J Exp Med. 1969 May 1;129(5):973–992. doi: 10.1084/jem.129.5.973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. McGregor D. D., Koster F. T. The mediator of cellular immunity. IV. Cooperation between lymphocytes and mononuclear phagocytes. Cell Immunol. 1971 Aug;2(4):317–325. doi: 10.1016/0008-8749(71)90066-9. [DOI] [PubMed] [Google Scholar]
  9. Pearson L. D., Osebold J. W. Effects of antithymocyte and antimacrophage sera on the survival of mice infected with Listeria monocytogenes. Infect Immun. 1973 Mar;7(3):479–486. doi: 10.1128/iai.7.3.479-486.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Simon H. B., Sheagren J. N. Cellular immunity in vitro. I. Immunologically mediated enhancement of macrophage bactericidal capacity. J Exp Med. 1971 Jun 1;133(6):1377–1389. doi: 10.1084/jem.133.6.1377. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES